Effect of the long acting ARB in hypertensive patients with cerebro vasucular disease not controlled by conventional therapy.
- Conditions
- Cerebrovasucular Disease, Hypertension
- Registration Number
- JPRN-UMIN000009825
- Lead Sponsor
- Tokyo Women's Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Not provided
1)Secondary hypertension 2)Severe hypertension with SBP>=180mmHg and/or DBP>=110mmHg 3)Malignant hypertension 4)Severe heart failure (NYHA III-IV) 5)Myocardial Infarction, Coronary bypass surgery, and PTCA were performed within 6 months 6)Patients contraindicated for the use of ARBs 7)Serum creatinine >=2.1mg/dL 8)Untreated hyperuricemia or serum uric acid>8mg/dL 9)Diabetes patients under insulin treatment, or HbA1c>9.0% 10)Patients with hypoglycemia 11)Patients who are inadequate by determination of physicians in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Central blood pressure
- Secondary Outcome Measures
Name Time Method Clinic BP 24hr BP on ABPM IMT(Intra Media Dilation) FMD(Flow Mediated Dilation) Control rate of Clinic BP Control rate of ABPM