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A Non-interventional, Post Marketing Surveillance (PMS) Study of Tresiba® (Insulin Degludec) to Evaluate Long Term Safety and Efficacy in Patients With Diabetes Mellitus in Routine Clinical Practice in India

Completed
Conditions
Diabetes Mellitus, Type 1
Diabetes
Diabetes Mellitus, Type 2
Interventions
Registration Number
NCT02117622
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This study is conducted in Asia. The aim of the study is to evaluate long term safety and efficacy of Tresiba® (insulin degludec) in patients with diabetes mellitus in routine clinical practice in India.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1056
Inclusion Criteria
  • Informed consent obtained before any study-related activities (Study related activities are any procedure related to recording of data according to the protocol). The historical data including the data before informed consent obtained (e.g. glycosylated haemoglobin (HbA1c), fasting plasma glucose (FPG), severe hypoglycaemia before the start of Tresiba® therapy) can be used for baseline data
  • Patients with insulin requiring diabetes mellitus and who is scheduled to start treatment with Tresiba® based on the clinical judgment of their treating physician
Exclusion Criteria
  • Known or suspected allergy to Tresiba®, the active substance or any of the excipients
  • Previous participation in this study
  • Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation
  • Patients who are or have previously been on Tresiba® therapy
  • Patients who are participating in other studies or clinical trials
  • Patients who are pregnant, breast feeding or have the intention of becoming pregnant within the following 12 months

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients with diabetes mellitus requiring insulin therapyinsulin degludec-
Primary Outcome Measures
NameTimeMethod
Incidence of adverse events (AEs) by preferred termDuring 1 year of treatment
Secondary Outcome Measures
NameTimeMethod
Incidence of serious adverse events (SAEs) by preferred termDuring 1 year of treatment
Incidence of serious adverse drug reactions (SADRs) by preferred termDuring 1 year of treatment
Incidence of adverse drug reactions (ADRs) by preferred termDuring 1 year of treatment
Incidence of severe hypoglycaemiaDuring 1 year of treatment
Change from baseline in glycosylated haemoglobin (HbA1c)Baseline (Visit 1, week 0), end of study (Visit 4, week 52)
Change from baseline in fasting plasma glucose (FPG)Baseline (Visit 1, week 0), end of study (Visit 4, week 52)
Incidence of confirmed hypoglycaemiaDuring 1 year of treatment

Trial Locations

Locations (1)

Novo Nordisk Investigational Site

🇮🇳

Thriruvananthapuram, India

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