Randomised double-blind, placebo-controlled, cross-over trial to determine the responsiveness of the gut microbiota to a prebiotic supplement in healthy individuals with differing habitual dietary fibre intakes

Genelle Healey0 个研究点目标入组 40 人开始时间: 2015年9月3日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•The target population for recruitment are healthy male and female individuals between the age of 19 and 65 years with a BMI of between 18.5 and 30kg/m2. Individuals will need to have either a particularly low or high habitual dietary fibre intake to be considered eligible to participate in the study.

•* Aged <19 or >65 years
•* Taken antibiotics within the last 6 months
•* Taken laxatives, gastric motility medications, prebiotic or probiotic containing foods or supplements within the last month
•* Of poor health- cancer, gastrointestinal disorders (irritable bowel syndrome, inflammatory bowel disease, coeliac disease, constipation, diarrhoea, excessive bloating), autoimmune disorders, diabetes, heart disease, renal failure
•* BMI <18.5 or >30kg/m2
•* Significant weight loss or weight gain (>5%) within the past year
•* Significant dietary change within the past year
•* Pregnant, breastfeeding or planning a pregnancy
•* Food intolerance which causes gastrointestinal symptoms (i.e. lactose intolerance, gluten sensitivity)
•* High alcohol consumers
•If a potential participant is only ineligible to participate in the study because they are taking prebiotic or probiotic containing foods or supplements they can become eligible for inclusion in the study if they are willing to discontinue these foods or supplements for a month prior to starting the study and during the study.

发起方

Genelle Healey