Predictors of Mortality in Patients With Autoimmune Diseases Admitted to the Intensive Care Unit - Retrospective Analysis at a Single Tertiary Care Center
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- In-hospital mortality
研究概览
简要总结
Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, myositis, or anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, may affect multiple organ systems. Occasionally, patients deteriorate acutely requiring advanced care in an intensive care unit (ICU). In an ICU setting, mortality is estimated with scoring systems, such as APACHE or SAPSII. Since there are limited data available on their use in autoimmune diseases, with the current study, we aim to assess the usefulness of these ICU scores and analyze predictors of mortality in this particular group of patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to the ICU at the University Medical Center Göttingen
排除标准
- •Patients with incomplete or missing data
研究组 & 干预措施
ANCA-associated Vasculitis
Patients with ANCA-associated vasculitis admitted to the ICU
干预措施: ICU Care (Other)
结局指标
主要结局
In-hospital mortality
时间窗: From date of admission to the ICU until the date of death from any cause assessed up to 52 weeks
次要结局
- Risk of renal replacement therapy(From date of admission to the ICU until the date of event assessed up to 52 weeks)
- Need for catecholamines(From date of admission to the ICU until the date of event assessed up to 52 weeks)
- Need for ventilation(From date of admission to the ICU until the date of event assessed up to 52 weeks)
- Need for cardiopulmonary resuscitation(From date of admission to the ICU until the date of event assessed up to 52 weeks)
研究者
Peter Korsten
Attending Physician, Head of the Rheumatology Clinical Trials Unit, Prinicipal Investigator
University of Göttingen