Comparison Between the Analgesic Effects of Ultrasound-guided Unilateral Quadratus Lumborum Block (Lateral Approach) Versus Erector Spinae Plane Block in Patients Undergoing Unilateral Lower Abdominal Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- morphine consumption
研究概览
简要总结
the purpose of study is comparison between the analgesic effect of two techniques in adult lower abdominal surgeries
详细描述
the study will be performed from November 2021 to January 2023 at Fayoum University hospital after approval of the local institutional ethics committee and local institutional review board .A detailed informed consent will be signed by the eligible participants before recruitment and randomization.
Preoperative preparations and Premedication :•
Both groups will be assessed by history taking, careful examination ,and laboratory investigations like:
Complete blood count (CBC), coagulation profile:(prothrombin concentration(PC),Partial thromboplastin time(PTT),International Normalized Ratio(INR) ) , kidney function, liver function, ECG for patient >40 years old or indicated cases, specific investigations to each disease
.•the investigators will teach the patients Visual Analogue Score (VAS) and train them.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
盲法说明
Randomization will be done by random sequence number generated by the computer kept in sealed envelopes. Those envelopes will be opened on the day of surgery when the patient is in the operating room and participant will receive either (QLB) or (ESPB) as per the envelope.
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients age 18-60 years old.
- •Patients scheduled for elective abdominal surgeries
- •ASA classification I, II.
- •Ability to sign the consent.
排除标准
- •Patient refusal.
- •Coagulation disorders.
- •Skin lesions or infection at site of proposed needle.
- •Known allergy to local anesthetics, or opioids.
- •Patients suffering from neurological or mental disease.
- •Opioid consumption 48 hours before the operation.
- •Sever Obesity body mass index(BMI) >35
- •Difficulty in Ultrasonographic identification.
研究组 & 干预措施
(QL) group
In (QL) group, (lateral Approach) :patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Bupivacaine Hydrochloride (Drug)
(QL) group
In (QL) group, (lateral Approach) :patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Ultrasound device (Device)
(QL) group
In (QL) group, (lateral Approach) :patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Dexamethasone (Drug)
(QL) group
In (QL) group, (lateral Approach) :patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: echogenic needle (Device)
(ESB) group
In (ESB) group, Erector Spinae Plane Block: patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Bupivacaine Hydrochloride (Drug)
(ESB) group
In (ESB) group, Erector Spinae Plane Block: patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Ultrasound device (Device)
(ESB) group
In (ESB) group, Erector Spinae Plane Block: patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: Dexamethasone (Drug)
(ESB) group
In (ESB) group, Erector Spinae Plane Block: patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone
干预措施: echogenic needle (Device)
结局指标
主要结局
morphine consumption
时间窗: 24 hours after the end of operation
Millie gram
次要结局
- Pruritus(24hours after operation)
- Ease of performance.(during performance of the block)
- vomiting(24hours after operation)
- patient satisfaction(24 hours after operation)
- Bowel injury(24hours after operation)
- intra vascular injection(24hours after operation)
- Hematoma formation(24hours after operation)
- Nausea(24hours after operation)
研究者
Rana Ahmed Abdelghaffar
lecturer of anesthesiology
Fayoum University Hospital