A Pilot Study on Usefulness of Probe-based Confocal Laser Endomicroscopy Targeted Gastric Biopsy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The percentage of cancer cells in biopsy samples
研究概览
简要总结
The purpose of this study is to conduct a study on genetic pathology, obtaining of pure cancer tissues is mandatory. Although the endoscopy with biopsy has been a gold standard for diagnosing gastric cancer, percentage of cancer cells in biopsy samples is usually 30% or less. Recently, confocal laser endomicroscopy has been introduced for real-time histopathologic diagnosis in various cancers. The investigators aim to evaluate that biopsy using probe-based confocal laser endomicroscopy will increase the percentage of cancer cells in biopsy samples.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age, between 20 and 80
- •Initial-onset gastric cancer which would be treated with surgery
排除标准
- •Previous subtotal gastrectomy
- •Pregnancy or breast milk feeding
- •Active infection
- •Significant cardiopulmonary disease
- •Active hepatitis or severe hepatic dysfunction
- •Severe renal dysfunction
- •Severe bone marrow dysfunction
- •Severe neurologic or psychotic disorder
研究组 & 干预措施
Probe-based confocal laser endomicroscopy
干预措施: Probe-based confocal laser endomicroscopy (Procedure)
White light endoscopy
干预措施: White light endoscopy (Procedure)
结局指标
主要结局
The percentage of cancer cells in biopsy samples
时间窗: After 3 days from the end of the endoscopic submucosal dissection
The percentages of cancer cells in biopsy samples according to the method of endoscopic method, probe-based confocal laser endomicroscopy versus white light endosocpy
次要结局
未报告次要终点