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临床试验/NCT07397221
NCT07397221尚未招募不适用

The Effect of Oropharyngeal Humidification After Extubation on Thirst, Pain, and Anxiety in Patients Undergoing Coronary Artery Bypass Surgery: A Randomized Controlled Study

Muş Alparslan University1 个研究点 分布在 1 个国家目标入组 42 人开始时间: 2026年2月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
42
试验地点
1
主要终点
Thirst Severity

研究概览

简要总结

In patients who have undergone endotracheal intubation following cardiac surgery, symptoms such as thirst, dysphagia (difficulty swallowing), restlessness, nausea, and vomiting are frequently observed, and these conditions negatively affect the patients' overall comfort. Especially in the post-intubation period, dryness in the mouth and throat, an intense feeling of thirst, and difficulty swallowing can lead to feelings of suffocation, helplessness, fear, and anxiety in patients. Effective management of these symptoms is critically important both for accelerating the recovery process and for increasing patient satisfaction.

Traditionally, methods such as moistening the mouth with a cotton swab have been used to relieve complaints like thirst and dry mouth. However, these practices are often insufficient and have limited effectiveness in increasing patients' comfort. In recent years, the use of oropharyngeal sprays has emerged as an innovative and effective approach to alleviate symptoms such as thirst and dry mouth. In a randomized controlled trial conduct, it was shown that a spray-based oropharyngeal moisturizing program significantly reduced the severity of thirst and discomfort in patients who underwent intubation after cardiac surgery. Thirst and discomfort scores were found to be significantly lower in the spray-applied groups compared to the control group, and no significant difference was observed between the groups in terms of dysphagia frequency or adverse events. Similarly, studies conducted in different surgical and intensive care populations have shown that applications of cold water or cold saline sprays significantly reduce complaints of thirst and dry mouth, increase patient comfort, and are safe to use.

Additionally, it has been reported that alternative approaches such as menthol lozenges or aromatherapy also have positive effects on thirst, nausea, and comfort after cardiac surgery. Examining the effects of oropharyngeal sprays and similar practices on parameters such as thirst, dysphagia, discomfort, nausea, vomiting, and overall comfort in patients who are intubated after cardiac surgery may contribute to the development of innovative and effective approaches in patient care. Integrating such practices into postoperative care protocols carries significant potential for increasing patient comfort and supporting the recovery process.

This randomized controlled study aims to investigate the effects of oropharyngeal humidification after extubation on thirst, pain, and anxiety in patients undergoing coronary artery bypass surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18-65
  • Undergoing coronary artery bypass surgery
  • Postoperative mechanical ventilation and extubation
  • Able to provide informed consent

排除标准

  • Neuromuscular diseases (e.g., stroke, Parkinson's disease)
  • Head/neck deformities
  • Pre-existing dysphagia
  • Tracheostomy
  • Inability to participate in assessments

研究组 & 干预措施

Oropharyngeal Humidification

Experimental

Participants in this arm will receive oropharyngeal humidification with room-temperature drinking water spray. After tracheal extubation, the researcher applies the spray to multiple oral regions (upper jaw, lower jaw, left cheek, right cheek, tongue) twice per hour for 4 hours.

干预措施: Oropharyngeal Humidification with Water Spray (Other)

Routine Oral Care

No Intervention

Participants receive only routine oral care provided in the ICU. Nurses use standard methods such as moistening the mouth with wet cotton swabs or lip wetting as needed.

结局指标

主要结局

Thirst Severity

时间窗: Baseline (immediately after extubation) 2 hours post-intervention 4 hours post-intervention

The Numeric Rating Scale is used for patients to indicate the severity of their thirst. Patients will be asked to rate their feeling of thirst on a scale from 0 to 10. A score of 0 means no thirst at all. An increase in the score indicates increasing thirst. A score of 10 represents extreme thirst.

次要结局

  • Thirst-Related Discomfort(Baseline (immediately after extubation) 2 hours post-intervention 4 hours post-intervention)
  • Pain Severity(Baseline (immediately after extubation) 2 hours post-intervention 4 hours post-intervention)
  • Anxiety Level(Baseline (immediately after extubation) 2 hours post-intervention 4 hours post-intervention)
  • Post-Extubation Complications(Continuous monitoring during the 4-hour intervention period)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

tasci

Ph.D.

Muş Alparslan University

研究点 (1)

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