Efficacy of Zinc in the Treatment of Pneumonia

Not Applicable

Completed

• Conditions: Pneumonia
• Interventions: Drug: Zinc

• Registration Number: NCT00198666
• Lead Sponsor: Johns Hopkins Bloomberg School of Public Health

Brief Summary

This study is designed to evaluate the efficacy of zinc supplementation in the treatment of children under the age of two years who have been hospitalized with severe pneumonia.

Detailed Description

This study was a randomized, double-blind, placebo-controlled clinical trial conducted between September 2003 and August 2004 at the Christian Medical College (CMC) Hospital in Vellore, India. CMC Hospital is a large teaching hospital and medical center that is accessed directly by the population of Vellore and adjoining districts and by referrals from local medical practitioners.

Study Timeline

• Study Start: 2003-09
• Primary Completion: 2004-08
• Study Completion: 2004-08
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Study First Posted: 2005-09-20
• Status Verified: 2015-01
• Last Update Submitted: 2015-01-09
• Last Update Posted: 2015-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 299

Inclusion Criteria

• children under two years old hospitalized with Pneumonia

Exclusion Criteria

• healthy children

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment	Zinc	Children with severe pneumonia were randomly assigned to receive supplementation with elemental zinc.

Primary Outcome Measures

Name	Time	Method
Duration of severe symptoms	2 years

Secondary Outcome Measures

Name	Time	Method
Time to recovery from severe pneumonia	2 years