Efficacy of Zinc in the Treatment of Pneumonia in Hospitalized Children Less Than 2 Years of Age
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 299
- 主要终点
- Duration of severe symptoms
研究概览
简要总结
This study is designed to evaluate the efficacy of zinc supplementation in the treatment of children under the age of two years who have been hospitalized with severe pneumonia.
详细描述
This study was a randomized, double-blind, placebo-controlled clinical trial conducted between September 2003 and August 2004 at the Christian Medical College (CMC) Hospital in Vellore, India. CMC Hospital is a large teaching hospital and medical center that is accessed directly by the population of Vellore and adjoining districts and by referrals from local medical practitioners.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- — 至 23 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children under two years old hospitalized with Pneumonia
排除标准
- •healthy children
研究组 & 干预措施
Treatment
Children with severe pneumonia were randomly assigned to receive supplementation with elemental zinc.
干预措施: Zinc (Drug)
结局指标
主要结局
Duration of severe symptoms
时间窗: 2 years
次要结局
- Time to recovery from severe pneumonia(2 years)
研究者
Mathuram Santosham
Professor
Johns Hopkins Bloomberg School of Public Health