The effect of low dose Dexmedetomidine to prolong spinal anesthesia in elderly patients

Phase 1

Recruiting

• Conditions: Elderly (60-80 years old) undergoing Transurethral Resection of the Prostate under spinal anesthesia; dexmedetomidine, elderly, Transurethral Resection of the Prostate, TURP, spinal anesthesia, prolong, intravenous

• Registration Number: TCTR20240404001
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-10-06
• Study Start: 2024-04-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 38

Inclusion Criteria

1.Age 60-80 years
2.ASA physical status 1-3
3.undergoing Transurethral Resection of the Prostate under spinal anesthesia
4.inform consent before
5.pass cut-off point of MMSE-Thai 2002 for cognitive impairment

Exclusion Criteria

1.patient refuse to participate
2.contraindication to spinal anesthesia
3.allergy to drug in trial
4.liver cirrhosis
5.end stage renal disease
6.Bradycardia ((heart rate <=50 bpm))

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Two-dermatome regression until Two-dermatome regression Two-dermatome regression test every 10 min

Secondary Outcome Measures

Name	Time	Method
Visual analog scale 0, 6, 12, 24 hours Visual analog scale