Role of Spectrophotometer in Early Prediction of Weaning Induced Cardiac Dysfunction
- Conditions
- Weaning Failure
- Registration Number
- NCT06674824
- Lead Sponsor
- Ain Shams University
- Brief Summary
Weaning induced cardiac dysfunction is a common cause of weaning failure in critically ill patients. plethysmography variability index (PVI) is a non-invasive, real-time, and automated parameter for evalu¬ating fluid responsiveness.
By proving the validity of (PVI) in predicting successful spontaneous breathing trial Massimo can be used an easy noninvasive method that help in deciding the right time for weaning.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
- Intubation and mechanical ventilation
- Fulfilling criteria for extubation
- Fraction inspired oxygen less than 50%
- a. Hemodynamic instability b. b. tracheostomy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method accuracy of change PVI in detecting volume responsiveness 1 hour accuracy of change PVI in detecting volume responsiveness through measuring limits of agreement , Bias and correlation between PVI and a standard method of measurement which left ventricular outflow tract velocity time integral
- Secondary Outcome Measures
Name Time Method Sensitivity of trend of changes in hemoglobin by Massimo to detect WIPO and 1 hour time in minutes between rise of hemoglobin and clinical diagnosis of WIPO 1 hour minutes between rise of blood hemoglobin concentration measured by Massimo and clinical diagnosis of WIPO
Trial Locations
- Locations (1)
Ain Shams University hospitals
🇪🇬Cairo, Egypt