CTRI/2023/09/057178尚未招募4 期
A comparative study on safety and efficacy of intralesional tranexamic acid versus 50% glycolic acid chemical peel in the treatment of melasma
Madeshwari M1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年8月9日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To assess the resolution of hyperpigmentation
研究概览
简要总结
Melasma is a common acquired hyperpigmentation disorder, various treatment modalities are available
Management is difficult because it’s frequent relapse.
Recently studies shows intralesional tranexamic acid a hemostatic agent,has hypopigmentary effect on melasma lesions
Hence, my aim of study is to compare safety and efficacy of intralesional tranexamic acid versus 50%glycolic acid chemical peel
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to participate in the study.
排除标准
- •Before starting the study Pregnant & lactating mothers Patients on oral contraceptive pills, hormonal replacement therapy Active infection /inflammationPhotosensitivity disorders (SLE, porphyria) History of bleeding disorder /Anticoagulant treatment History of allergy Any other mode of treatment for melasma prior to the study During the Study: Develops side effects during the treatment patient wants to discontinue the treatment.
结局指标
主要结局
To assess the resolution of hyperpigmentation
时间窗: Baseline,week 4, week 8, week 12 and week 24
次要结局
- To assess modified MASI score(Baseline, week 12 and week 24)
研究者
研究点 (1)
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