Intraoperative fluid therapy for patients undergoing elective liver resectio

Phase 4

Completed

• Conditions: iver resection surgery; Intravenous fluid therapy; Acid-base physiology; Liver resection surgery; Anaesthesiology - Anaesthetics; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12610000147088
• Lead Sponsor: Austin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult patients having elective liver resection surgery

Exclusion Criteria

1. Patient declines to take part
2. Age less than 18 years
3. Abnormal pre-operative coagulopathy: INR (international normalised ratio) > 1.4, platelet count < 75 x 109/l
4. Severe hepatic insufficiency (bilirubin > 30umol/L, ALP (alkaline phosphatase) >300iu/L, ALT (alanine transaminase) > 50iu/L, albumin < 25g/dL, INR > 1.5
5. Moderate/severe renal impairment: serum creatinine > 200ummol/l
6. Hyperkalaemia (serum potassium > 5.6)
7. American Society of Anaesthesiologists (ASA) physical status IV or V
7. Patients with a known previous allergic reaction to study solutions

Study & Design

• Study Type: Interventional
• Study Design: Not specified