Biobank Cardiac Surgery

Recruiting

• Conditions: Cardiovascular Diseases

• Registration Number: NCT06747806
• Lead Sponsor: University of Chicago

Brief Summary

Treatment strategies for cardiac surgery patients have been evolving significantly for the last decade. While clinical outcomes have been improving, there are still significant areas unexplored in these patients. Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, rheumatic heart disease, and atherosclerosis.

Biobanking is a fundamental process required in the better understanding of human diseases together with their underlying mechanisms. Biobanking refers to the process by which samples of bodily fluid or tissue are collected for research use to improve the understanding of health and disease. For this study, the investigator's objective is to acquire elucidation in disease etiology, translation, and advancing public health by evaluating blood and tissue results of those with cardiac disease undergoing cardiac surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-18
• Status Verified: 2024-11
• Study First Submitted: 2024-11-22
• Study First Submitted QC: 2024-12-17
• Last Update Submitted: 2024-12-17
• Study First Posted: 2024-12-24
• Last Update Posted: 2024-12-24
• Primary Completion: 2028-12
• Study Completion: 2028-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• All patients who undergo cardiac surgery at Advocate Children's Hospital (ACH)& University of Chicago Medical Center (UCMC) by the ACH & UC Cardiothoracic Surgery Research team who are pediatric neonates and up.
• Patients will only be English speaking.

Exclusion Criteria

• Vulnerable Subjects/Subject Capacity to provide consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concentration of the elucidation in disease etiology from evaluating blood and tissue results	From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 100 months	To acquire elucidation in disease etiology health by evaluating blood and tissue results of those with cardiac disease undergoing cardiac surgery.
Concentration of the elucidation in disease translation from evaluating blood and tissue results	From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 100 months	To acquire elucidation in disease translational health by evaluating blood and tissue results of those with cardiac disease undergoing cardiac surgery.
Concentration of the elucidation in advancing public health by evaluating blood and tissue results	From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 100 months	To acquire elucidation in advancing public health by evaluating blood and tissue results of those with cardiac disease undergoing cardiac surgery.

Trial Locations

Locations (1)

The University of Chicago; 🇺🇸 Hyde Park, Illinois, United States