Comparative efficacy of intra-lesional bleomycinsulphate and Immunotherapy with Candida skin testing antigen in the treatment of palmoplantar warts

INDIAN COUNCIL OF MEDICAL RESEARCH0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•1.Age- Adult males and females aged 18-65 years.
•2.Multiple plantar warts diagnosed on the basis of history and physical examination by two dermatologists.
•Palmoplantar warts will be defined as sharply defined, hyperkeratotic rough lesions with loss of epithelial ridges over the surface of the lesion with a smooth collar of thickened horn present over the palmar or plantar surfaces.
•3.Untreated or no treatment in the last four weeks.

•1.Known immune-compromised state such as history of HIV infection, on steroids and other immunosuppressive drugs.
•2.Past history of immunotherapy or bleomycin sulphate.
•3.Warts measuring more than 20cm2 in size.
•4.Local site infection.
•5.Pregnant and lactating females.
•6.Any history of chronic cardiac, renal and pulmonary illness, peripheral vascular disease, Raynaudâ??s disease.
•7.Unable to give informed consent.
•8.Allergy to components of candida antigen or bleomycin sulphate.

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