CTRI/2020/12/029888RecruitingPhase 3
status and effect of pancreatic enzyme replacement therapy on gut microbiota and resting energy expenditure in patients with chronic pancreatitis
ICMR0 sites0 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •1.Idiopathic chronic pancreatitis
- •2.With or without pancreatic exocrine insufficiency
- •3.Participants giving the consent
- •Healthy Controls:
- •1.Relative of the patient
- •2.In good general health with no co morbidities(diabetes, IBD, IBS etc)
- •3.No pregnancy
- •4.No calorie restriction or other special diets
- •5.No known allergy
- •6.Not on medical treatment influencing intestinal function
- •7.No alcohol ( intake more than 2 pegs a day)
- •8.No smoking
Exclusion Criteria
- •1.Concomitant medical disorder which are supposed to influence the gut microbiota like HIV, any malignancy, inflammatory bowel disease, irritable bowel syndrome, gastroenteritis, liver disease.
- •2.Pregnancy
- •3.Medical treatment influencing intestinal function
- •4.Subjects received antibiotics in last 3 months
- •5.Patients who are taking proton pump inhibitor
- •6.Chronic pancreatitis with another complication( symptomatic pseudocyst or GI bleed)
- •7.Severe pain score:16 or more
Investigators
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