A comparative study between Spasm relieving medications, Clonazepam and Baclofen given orally in spinal cord injury patients.
Phase 3
- Conditions
- Health Condition 1: S140- Concussion and edema of cervical spinal cordHealth Condition 2: S340- Concussion and edema of lumbar andsacral spinal cordHealth Condition 3: S240- Concussion and edema of thoracic spinal cordHealth Condition 4: S141- Other and unspecified injuries ofcervical spinal cordHealth Condition 5: S241- Other and unspecified injuries ofthoracic spinal cordHealth Condition 6: S341- Other and unspecified injury of lumbar and sacral spinal cord
- Registration Number
- CTRI/2022/12/047966
- Lead Sponsor
- Bharat Pulavarti
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Spinal cord injury patients in the above age group, suffering from spasms, have sufficient mental capacity to respond relevantly to all queries related to spasms.
Exclusion Criteria
Spinal cord injury patients who exhibit spasticity but do not present with spasms.
Patients who are pregnant.
Patients with narrow angle glaucoma.
Patients with history of clinical depression and suicidal tendencies. Patients who are currently on antispastic and anti-spasm medication will not be enrolled in the study.
Patients with deranged complete blood count, liver function tests and renal function tests.
Patients with pre-existing musculoskeletal disorders and movement disorders in which spasms and spasticity cannot be assessed accurately.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in problematic spasms assessed by Penn spasm frequency and severity scale by at least one grade.Timepoint: The final assessment will be done on the 31st day after the initiation of the intervention
- Secondary Outcome Measures
Name Time Method To determine the proportion of patients who benefitted from each intervention.Timepoint: Final assessment on 31st day after initiation of the intervention.