The Clinical research for recurrent spontaneous abortion treated by Qing-Yi Tiao-Mian formula

Not Applicable

Recruiting

• Conditions: Recurrent Spontaneous Abortion

• Registration Number: ITMCTR1900002572
• Lead Sponsor: Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

2 or more spontaneous abortions occurred within 12 weeks gestation

Exclusion Criteria

1) The genetic abnormality of both husband and wife, the male semen abnormalities lead to RSA;
2) severe diseases such as cerebrovascular, hepatic, renal and hematopoietic system;
3) Excluding uterine fibroids, uterine malformations and other anatomical abnormalities leading to RSA;
4) Excluding endometrial receptivity abnormalities such as intrauterine adhesions leading to RSA;
5) Exclude congenital prethrombotic state such as coagulation factor gene mutation leading to RSA;
6) Exclude acquired prethrombotic state such as antiphospholipid syndrome leading to RSA;
7) Exclude endocrine diseases such as polycystic ovary syndrome and gestational diabetes leading to RSA; Those who are allergic to research drugs, have a history of drug-induced liver damage.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pregnancy outcome;

Secondary Outcome Measures

Name	Time	Method
Distribution of Treg lymphocytes in endometrium during luteal phase;cytokines in peripheral blood;population of T lymphocytes in endometrium during luteal phase;population of T lymphocytes in peripheral blood;Distribution of CD8+T lymphocytes in endometrium during luteal phase;