Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 6,000
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
Aim of this project is to understand clinical features, clinical outcomes and efficacy and safety profiles of different therapies by analyzing a cohort of COVID-19 patients hospitalized and treated in a tertiary-level institution, University hospital Dubrava. Patients' clinical and laboratory characteristics, drug exposure and outcomes are obtained by analysis of written and electronical medical records.
详细描述
University Hospital Dubrava has been completely repurposed during the COVID-19 pandemic to become high volume COVID-19 tertiary institution. Establishment of hospital registry project is necessary to properly understand disease characteristic, related outcomes and real-life treatment patterns. Registry provides a fundamental framework for future upgrading with emerging or retrogradely obtained specific data that will substantially facilitate understanding of COVID-19 in the context of other specific diseases, therapies and procedures. Large comprehensive database will provide sufficient statistical power to allow for investigation of large number of subgroups and existence of interactions between different variables. Assessment of large number of clinically important outcomes (mortality, occurrence of venous and arterial thromboses, major bleeding, bacteriemia, incidence of mechanical ventilation and intensive care unit admission) is necessary to put any investigated parameter in the proper efficacy and safety context.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all hospitalized patients positive for COVID-19
排除标准
- 未提供
结局指标
主要结局
Mortality
时间窗: At 30-days from hospital admission
Incidence of death from any cause
次要结局
- Incidence of mechanical ventilation(At 30-days from hospital admission)
- Incidence of venous or arterial thrombotic events(At 30-days from hospital admission)
- Incidence of major bleeding(At 30-days from hospital admission)
- Incidence of intensive care unit admission(At 30-days from hospital admission)
- Incidence of bacteriemia(At 30-days from hospital admission)
研究者
Marko Lucijanić
Study Director
University Hospital Dubrava
