Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- University Hospital Dubrava
- Enrollment
- 6000
- Locations
- 1
- Primary Endpoint
- Mortality
- Status
- Active, Not Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Aim of this project is to understand clinical features, clinical outcomes and efficacy and safety profiles of different therapies by analyzing a cohort of COVID-19 patients hospitalized and treated in a tertiary-level institution, University hospital Dubrava. Patients' clinical and laboratory characteristics, drug exposure and outcomes are obtained by analysis of written and electronical medical records.
Detailed Description
University Hospital Dubrava has been completely repurposed during the COVID-19 pandemic to become high volume COVID-19 tertiary institution. Establishment of hospital registry project is necessary to properly understand disease characteristic, related outcomes and real-life treatment patterns. Registry provides a fundamental framework for future upgrading with emerging or retrogradely obtained specific data that will substantially facilitate understanding of COVID-19 in the context of other specific diseases, therapies and procedures. Large comprehensive database will provide sufficient statistical power to allow for investigation of large number of subgroups and existence of interactions between different variables. Assessment of large number of clinically important outcomes (mortality, occurrence of venous and arterial thromboses, major bleeding, bacteriemia, incidence of mechanical ventilation and intensive care unit admission) is necessary to put any investigated parameter in the proper efficacy and safety context.
Investigators
Marko Lucijanić
Study Director
University Hospital Dubrava
Eligibility Criteria
Inclusion Criteria
- •all hospitalized patients positive for COVID-19
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Mortality
Time Frame: At 30-days from hospital admission
Incidence of death from any cause
Secondary Outcomes
- Incidence of mechanical ventilation(At 30-days from hospital admission)
- Incidence of venous or arterial thrombotic events(At 30-days from hospital admission)
- Incidence of major bleeding(At 30-days from hospital admission)
- Incidence of intensive care unit admission(At 30-days from hospital admission)
- Incidence of bacteriemia(At 30-days from hospital admission)