The effect of vaginal sildenafil on endometrial thickness and pregnancy rates in infertile wome
Phase 3
Recruiting
- Conditions
- Female infertility.Female infertility, unspecifiedN97.9
- Registration Number
- IRCT20210110049997N1
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
The number of sperm in female spouses is between 5-10 million.
Sperm motility of female spouses should be between 25-30%.
The normal morphology of female spouses sperm is between 3-4%.
Women's body mass index should be less than 40.
Endometrial thickness less than 7 mm.
Exclusion Criteria
Hypotension
History of endocrine diseases
History of stroke or heart attack
Cardiovascular problems
Consumption of nitrites or nitrates
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial thickness. Timepoint: Measurement of endometrial thickness at the beginning of the study (before the start of the intervention, which should be less than 7 mm) and 14 days after the start of taking an oral estradiol tablet and a sildenafil vaginal tablet. Method of measurement: Ultrasound device.
- Secondary Outcome Measures
Name Time Method