Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins

Not Applicable

• Conditions: Cesarean Section Complications
• Interventions: Procedure: bilateral uterine artery ligation; Drug: Oxytocin

• Registration Number: NCT04518176
• Lead Sponsor: Aswan University Hospital

Brief Summary

Objective to assess the effectiveness of prophylactic bilateral uterine artery ligation (BUAL) in reducing the incidence of postpartum hemorrhage during cesarean delivery among women with twin pregnancy

Detailed Description

A randomized clinical trial at Aswan University Maternity Hospital, Egypt. Women with twin pregnancy undergoing scheduled or emergency cesarean were randomized into two groups. In the BUAL group, women underwent BUAL before placental delivery; in the control group, women had cesarean delivery without BUAL. The primary outcome was the estimated blood loss during a cesarean

Study Timeline

• Study First Submitted: 2020-08-15
• Study First Submitted QC: 2020-08-15
• Study First Posted: 2020-08-19
• Status Verified: 2020-09
• Study Start: 2020-09-01
• Last Update Submitted: 2020-09-18
• Last Update Posted: 2020-09-21
• Primary Completion: 2022-06-30
• Study Completion: 2022-08-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 400

Inclusion Criteria

• women undergoing cesarean section
• twin pregnancy

Exclusion Criteria

• Placenta previa.
• Ante-partum hemorrhage.
• patient refuse to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
study group	Oxytocin	patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.
control group	Oxytocin	patients with twin pregnancy undergoing cesarean section received oxytocin only.
study group	bilateral uterine artery ligation	patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.

Primary Outcome Measures

Name	Time	Method
mean Blood loss after placental separation	30 minutes	by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set

Secondary Outcome Measures

Name	Time	Method
Number of Participants with postpartum hemorrhage	12 hours	number pf participants with blood loss \> 1000ml
The number of participant needed for blood transfusion	24 hours	Calculation of the number of participant needed for blood transfusion

Trial Locations

Locations (1)

Aswan University Hospital; 🇪🇬 Aswan, Egypt