Study Effect of Ashwagandhadi Churnvati and Lakshadi Guggul in the management of Dhatukhsyajanya Sandhigatvat of Janu Sandhi

Phase 1/2

Not yet recruiting

• Conditions: Osteoarthritis of knee, unspecified,

• Registration Number: CTRI/2020/03/023874
• Lead Sponsor: Principal PDEAs College of Ayurved and Research center

Brief Summary

Dhatukshayjanya Sandhigatvat is thedisease well known since vedic period.

Dhatukshayjanya Sandhigatvat which isknown to world as Osteoarthritis of Knee joint.

Dhatukshayjanya Sandhigatvat in Janusandhi is one of such chronic degenerative inflammatary disease which has agreat impact on quality of life of an individual. Different modalities oftreatment have been explained in Ayurveda to tackle the condition effectively.

In India 20 million peoples aresuffered from Osteoarthritis. The prevalence rate of Osteoarthritis in India is28.7%. It is more common in women than in men but prevalence increasesdramatically with age.

Dhatukhsyajanya Sandhigatvat can becorrelated with Osteoarthritis on the basis of some common symptoms like Jointpain, stiffness, decreased range of motion, oedema.

In Ayurveda, effective management is described invarious AyurvedicSamhitas. Ayurveda has the best medicines and treatment optionsfor Osteoarthritis. If these treatments can be started at the beginning of thesymptoms, the degeneration can be prevented.

Hence there is a need of a drug explained inVangsenSamhitain Chikitsa adhay named as Ashwagandhadi Churnvati.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-01-22
• Study Start: 2020-03-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

• 1 patients diagnosed with Osteoarthritis(Dhatukhsyajanya sandhigatvat of Janusandhi) 2 age.
• 45 yrs to 75 yrs of age 3 Gender.
• Male and Female 4 Patients presenting with the classical signs and symptoms of Dhatukhsyajanya sandhigatvat janu Shula, janu Shotha, stambha, sparsha-asahyata, janu sandhi sphutana, aakunchanaprasarana vedana, vatapurnadrutisparsha 5 Patients without any Anatomical Deformity.

Exclusion Criteria

• 1 Patients below 45 yrs and above 75 yrs of age.
• 2 patients with known case of uncontrolled diabetes, rheumatoid arthritis ,psoriatic arthritis, gouty arthritis, systemic lupus erythematosus (SLE), bone Tuberculosis, injuries and other serious systemic disorders .
• 3 Fracture of knee joint.
• 4 Direct and indirect infection of knee joint.
• 5 History of any surgical procedure of knee joint.
• 6 Any anatomical deformity.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate efficacy of Ashwagandhadi Churnvati 1 gm at Vyanodan Kal with Koshnajal for 2 months is as effective as Lakshadi Guggul 500mg-2tab at Vyanodan Kal with Koshnajal for 2 months in Dhatukhsyajanya sandhigatvat of Janu Sandhi.	60 days with follow up on every 15th day

Secondary Outcome Measures

Name	Time	Method
1 To compare the efficacy of Ashwagandhadi churnvati	2 To compare the efficacy of Lakshadi guggul

Trial Locations

Locations (1)

Ayurved and Sterling Multispeciality Hospital; 🇮🇳 Pune, MAHARASHTRA, India

Ayurved and Sterling Multispeciality Hospital

🇮🇳Pune, MAHARASHTRA, India

Dnyaneshwar Laxman Sawant

Principal investigator

8975362309

sawantdnyaneshwar516@gmail.com