跳至主要内容
临床试验/NCT01855204
NCT01855204Unknown不适用

Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent: a Comparison Study With Conventional CT Urography

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2013年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
64
试验地点
1
主要终点
Measurement of Radiation Dose

研究概览

简要总结

Computed Tomographic (CT) urography is the best imaging modality to evaluate obstructing lesions of urinary tract such as urinary stone, tumor and inflammatory lesion. The purpose of our study is to compare images of CT urography performed by low voltage and low concentrated iodine CT contrast with them of conventional CT urography.

详细描述

Computed Tomographic (CT) urography is the best imaging modality to evaluate obstructing lesions of urinary tract such as urinary stone, tumor and inflammatory lesion. It is needed that CT urography should have the high contrast between target lesion described as filling defect and adjacent contrast filled urinary tract. For the implementation of high contras, conventional CT urography has been performed with higher voltage and higher concentrated CT contrast than another CT protocols. The higher voltage results in the more radiation exposure. And the intravenous injection of higher concentrated CT contrast results in the increase of the prevalence of contrast induced nephrotoxicity.

The purpose of our study is to compare images of CT urography performed by low voltage and low concentrated iodine CT contrast with them of conventional CT urography.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Patients to perform Computed Tomographic (CT) urography
  • •Patients without diminish of renal function (serum creatinine: more than 1.4 mg/dl & glomerular filtration rate: more than 34 mL/min/1.73 m2)

排除标准

  • •patients to have operations and/or injuries of urinary system
  • •patients to have the histories of anaphylaxis or allergic reaction about intravenous iodine contrast material

研究组 & 干预措施

Conventional

Active Comparator

Computed tomographic urography was done with conventional protocols.

干预措施: Computed tomographic urography (Radiation)

Reduced

Experimental

Computed tomographic urography was done with the protocols of low voltage and low iodine concentration.

干预措施: Computed tomographic urography (Radiation)

结局指标

主要结局

Measurement of Radiation Dose

时间窗: The day of admission (within 24hours)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jeong Yeon Cho

Professor

Seoul National University Hospital

研究点 (1)

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