NCT03629704
Unknown
Not Applicable
Relationship Between Blood Glucose Variability and Prognosis in Critically Ill Patients
ConditionsDiabetes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diabetes
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
- Enrollment
- 200
- Primary Endpoint
- 28 day prognosis
- Last Updated
- 7 years ago
Overview
Brief Summary
This study is to evaluate the glycemic variation using Continuous Glucose Monitoring System in patients in the intensive care unit, find out the occult hypoglycemia, and investigate the relationship between glycemic variation, especially the incidence of hypoglycemia and prognosis of patients. Meanwhile, the inflammatory factors were measured and the relationship between inflammatory factors and glycemic variation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with history of diabetes;
- •Patients without history of diabetes, but their random blood glucose≧7.8mmol/L or fast blood glucose≧5 mmol/L;
- •The patients hospitalized in care unit (ICU or CCU) for more than 48 hours.
Exclusion Criteria
- •Patient had history of mental illness;
- •Patient was not suitable for using the CGMS;
- •blood glucose \> 22.2 mmol/L at admission.
Outcomes
Primary Outcomes
28 day prognosis
Time Frame: 0-28 days
Case-fatality at 28 days
Secondary Outcomes
- Incidence of hypoglycemia(1-4 days)
- Acute Physiology and Chronic Health Evaluation II score(0-28 days)
- Global registry of acute coronary events risk score(0-28 days)
- Twenty-four-hour mean blood glucose(1-4 days)
- Mean amplitude of glycemic excursion every 24 h(1-4 days)
Similar Trials
Recruiting
Not Applicable
Characteristics of Blood Glucose Variability in Patients With Type 2 Diabetes Mellitus and COVID-19COVID-19 PneumoniaType2diabetesNCT06156137Qilu Hospital of Shandong University200
Completed
Not Applicable
Investigation Into the Effects of Blood Glucose Levels Upon Eating Behavior in Lean and Obese Non-diabetic and Diabetic SubjectsDiabetesNCT02673203Yale University31
Completed
Not Applicable
IGNITE (Impact of Glucose moNitoring and nutrItion on Time in rangE)Type 2 DiabetesNCT05516797HealthPartners Institute178
Unknown
Not Applicable
Relationship Between Blood Glucose Levels and Variability and Infections Development in Critically Ill PatientCritical CareNCT02659995Università Politecnica delle Marche3,300
Completed
Not Applicable
Glycaemic Markers in Persons With Type 2 Diabetes on Peritoneal DialysisHbA1cPeritoneal DiseasesGlycated AlbuminFructosamineContinuous Glucose MonitoringNCT04125160Rigshospitalet, Denmark54