Skip to main content
Clinical Trials/NCT06347913
NCT06347913
Not yet recruiting
Not Applicable

Umblical Artery Systolic \Diastolic Ratio and Amniotic Fluid Index in Prediction of Fetal

Sohag University1 site in 1 country213 target enrollmentApril 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Umblical Artery Doppler in Term Pregnancy
Sponsor
Sohag University
Enrollment
213
Locations
1
Primary Endpoint
Umbilical Artery Systolic/Diastolic Ratio
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

Antepartum fetal surveillance is the cornerstone of management in pregnancy. [1] It is done primarily to reduce the incidence of adverse fetal outcomes. It minimizes morbidity by optimizing the timing of delivery. Fetus at risk of chronic hypoxia is identified and unnecessary interventions are avoided. However, fetal surveillance acts as a diagnostic modality to detect the influence of maternal, placental, and fetal factors on the fetus. The timely detection of morbid changes in the fetal status followed by adequate interventions to avoid death or disability is one of the most important objectives of prenatal care. [2] Tests now commonly done for antepartum fetal surveillance are nonstress test (NST), amniotic fluid index (AFI), biophysical profile, Doppler study of umbilical artery (UA), and middle cerebral artery (MCA).[3 6] However, AFI and UA Doppler velocimetry both form an essential part of the antenatal surveillance in the assessment of fetal well being. UA Doppler is a powerful tool that allows the obstetrician to follow a sequence of fetal hemodynamic events that happen in response to placental insufficiency. [7] However, several studies have reported higher sensitivities and specificities for UA Doppler ratio for prediction of fetal prognosis. [3 6] Amniotic fluid is the product of complex and dynamic fetal and placental physiologic processes. Disruption of the fine balance may result in overproduction or underproduction of fluid. Liquor adequacy often reflects the fetal status. Oligohydramnios is associated with increased perinatal loss. Furthermore, other studies indicate that UA velocimetry is a predictor of adverse outcomes in pregnancies complicated by oligohydramnios. [8,9] Thus, arterial Doppler velocimetry measurement may be useful in predicting adverse pregnancy outcomes adjunct to other antenatal surveillance tests, especially the AFI. Therefore, the present study will be done to evaluate the comparative assessment of UA ratio and AFI in predicting adverse perinatal outcomes.

Registry
clinicaltrials.gov
Start Date
April 2024
End Date
March 2025
Last Updated
2 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sabrin Alnokrashy Mohamed

resident at obstetric and gynacology department at sohag university hospial

Sohag University

Eligibility Criteria

Inclusion Criteria

  • \* Age of mother 18-40 years
  • Term pregnancy (37w6d -40w)
  • Singleton pregnancy

Exclusion Criteria

  • \*Multiple pregnancy
  • Preterm pregnancy before 37w
  • Preeclampsia
  • Congenital anomalies of fetus

Outcomes

Primary Outcomes

Umbilical Artery Systolic/Diastolic Ratio

Time Frame: 6 months

Umblical Artery Systolic/Diastolic Ratio

Study Sites (1)

Loading locations...

Similar Trials