Umblical Artery Systolic \Diastolic Ratio and Amniotic Fluid Index in Prediction of Fetal
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Umblical Artery Doppler in Term Pregnancy
- Sponsor
- Sohag University
- Enrollment
- 213
- Locations
- 1
- Primary Endpoint
- Umbilical Artery Systolic/Diastolic Ratio
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Antepartum fetal surveillance is the cornerstone of management in pregnancy. [1] It is done primarily to reduce the incidence of adverse fetal outcomes. It minimizes morbidity by optimizing the timing of delivery. Fetus at risk of chronic hypoxia is identified and unnecessary interventions are avoided. However, fetal surveillance acts as a diagnostic modality to detect the influence of maternal, placental, and fetal factors on the fetus. The timely detection of morbid changes in the fetal status followed by adequate interventions to avoid death or disability is one of the most important objectives of prenatal care. [2] Tests now commonly done for antepartum fetal surveillance are nonstress test (NST), amniotic fluid index (AFI), biophysical profile, Doppler study of umbilical artery (UA), and middle cerebral artery (MCA).[3 6] However, AFI and UA Doppler velocimetry both form an essential part of the antenatal surveillance in the assessment of fetal well being. UA Doppler is a powerful tool that allows the obstetrician to follow a sequence of fetal hemodynamic events that happen in response to placental insufficiency. [7] However, several studies have reported higher sensitivities and specificities for UA Doppler ratio for prediction of fetal prognosis. [3 6] Amniotic fluid is the product of complex and dynamic fetal and placental physiologic processes. Disruption of the fine balance may result in overproduction or underproduction of fluid. Liquor adequacy often reflects the fetal status. Oligohydramnios is associated with increased perinatal loss. Furthermore, other studies indicate that UA velocimetry is a predictor of adverse outcomes in pregnancies complicated by oligohydramnios. [8,9] Thus, arterial Doppler velocimetry measurement may be useful in predicting adverse pregnancy outcomes adjunct to other antenatal surveillance tests, especially the AFI. Therefore, the present study will be done to evaluate the comparative assessment of UA ratio and AFI in predicting adverse perinatal outcomes.
Investigators
Sabrin Alnokrashy Mohamed
resident at obstetric and gynacology department at sohag university hospial
Sohag University
Eligibility Criteria
Inclusion Criteria
- •\* Age of mother 18-40 years
- •Term pregnancy (37w6d -40w)
- •Singleton pregnancy
Exclusion Criteria
- •\*Multiple pregnancy
- •Preterm pregnancy before 37w
- •Preeclampsia
- •Congenital anomalies of fetus
Outcomes
Primary Outcomes
Umbilical Artery Systolic/Diastolic Ratio
Time Frame: 6 months
Umblical Artery Systolic/Diastolic Ratio