Serum interleukin-6 (IL-6) levels in prognosticating postoperative complications after ovarian cancer surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Complications
研究概览
简要总结
Interleukin-6 (IL-6) is an acute phase cytokine, with a pro-inflammatory character. Raised serum IL-6 levels have been associated with acute and chronic inflammatory conditions including cancer. An elevated serum IL-6 level has been associated with an adverse prognosis in patients with different types of cancers, including ovarian cancer. Ovarian cancer surgery has shown to be associated with a high risk (up to 34%) of 30-day postoperative morbidity. This can significantly affect the hospital stay, costs and the psychological well-being of the patient. There are no studies evaluating the changes in the serum levels of IL-6 postoperatively in ovarian cancer surgery, and its relation to postoperative complications.
Our objectives are -
1.To determine if the serum level of interleukin-6 (IL-6) was elevated pre-operatively in patients with ovarian cancer in our patient population.
2.To determine if high serum levels of IL-6 post-operatively can predict increased postoperative morbidity due to postoperative complications.
We hypothesize that rise in serum IL-6 levels postoperatively, can help to prognosticate postoperative complications after ovarian cytoreductive surgery.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- Female
入选标准
- •All Carcinoma Ovary patients posted for ovarian cytoreduction surgery will be included.
排除标准
- •Patients posted for emergency procedures will be excluded Patients who refuse to consent.
结局指标
主要结局
Complications
时间窗: During hospital stay
Mortality
时间窗: During hospital stay
次要结局
- Length of ICU stay(Length of Hospital stay)