Deep Learning in Vascular and Structural Retinal Changes in Diabetic Patients Undergoing Artificial Pancreas Device
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 11
- Locations
- 1
- Primary Endpoint
- The measurements of retinal and choriocapillary vessel density in type 1 diabetic patients undergoing artificial pancreas device
Study Overview
Brief Summary
This study evaluates the ability of deep learning to improve the knowledge about structural and vascular retinal changes in diabetic patients undergoing artificial pancreas device, using optical coherence tomography angiography.
Detailed Description
hybrid artificial pancreas systems (CSII) are able to adjust the type 1 diabetic patient's glycemic levels with insulin doses appropriate to the patient's blood glucose.
The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed and quantitative analysis of retinal and choriocapillary vascular features.
The study evaluates the changes in optical coherence tomography angiography features in diabetic patients undergoing artificial pancreas device, elaborating these data with artificial intelligence.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •• age older than 18 years
- •diagnosis of type 1 diabetes
- •treatment with artificial pancreas device
- •absence of previous ocular surgery and congenital eye diseases.
- •absence of errors of refraction
- •absence of lens opacities
- •absence of low-quality OCT and OCTA images
Exclusion Criteria
- •age younger than 18 years
- •previous ocular surgery and congenital eye diseases
- •errors of refraction
- •lens opacities
- •low-quality OCT and OCTA images
Outcomes
Primary Outcomes
The measurements of retinal and choriocapillary vessel density in type 1 diabetic patients undergoing artificial pancreas device
Time Frame: up to 3months
The parameters analyzed by optical coherence tomography angiography were: retinal and choriocapillary vessel density matched with clinical parameters resulted from the artificial pancreas device
Secondary Outcomes
No secondary outcomes reported
Investigators
Ciro Costagliola
professor
Federico II University