Congenital Cataract Morphological Classifications and Monitoring Using Slit-Lamp-Adapted Photography in CCPMOH
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 1,050
- Locations
- 1
- Primary Endpoint
- Congenital Cataract Morphological Classifications and Monitoring using Slit-Lamp-Adapted Photography
Study Overview
Brief Summary
Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology.This study is to investigate the feasibility of congenital cataract morphological classifications and monitoring using slit-lamp-adapted anterior segmental photography in a large cohort that included uncooperative children.
Detailed Description
Lens opacities in congenital cataracts have a wide range of presentations.Therefore, it is important to find a method of recording, classifying and monitoring cataract morphologies that is feasible and safe in a large cohort of children with congenital cataracts, including uncooperative children. Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology.
In this study, the investigators studied congenital cataract morphological classifications and monitoring using slit-lamp-adapted anterior segmental photography and evaluated its safety and feasibility in pediatric cataract patients registered in the Childhood Cataract Program of the Chinese Ministry of Health.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- — to 10 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Children with pediatric unilateral/bilateral cataracts
- •Children who were younger than 10 years of age
Exclusion Criteria
- •Premature birth
- •Microphthalmia
- •Micro-or Megalocornea
- •Keratoconus
- •Traumatic or complicated cataracts
- •Vitreous and retinal diseases
- •Any previous surgeries, and contraindication for pupil dilation and sedation
Arms & Interventions
eligible patients group
Intervention: slit-lamp-adapted anterior segmental photography (Procedure)
Outcomes
Primary Outcomes
Congenital Cataract Morphological Classifications and Monitoring using Slit-Lamp-Adapted Photography
Time Frame: baseline
All eligible pediatric patients underwent pupil dilation with compound tropicamide eye drops 3 times (1 time every 10 minutes) before the examination or administration of sleep aid medicine. Then, the children underwent slit-lamp-adapted anterior segmental photography (BX900, Haag-Streit AG, Köniz, Switzerland) for each cataractous lens, including one diffuse light photo, one slit-light photo across the cataract and one retro-illumination photo. All photos of the included patients were screened and morphologically classified separately by two pediatric ophthalmologists; a third ophthalmologist was masked and required to make a decision if the first two physicians had different opinions.
Secondary Outcomes
No secondary outcomes reported
Investigators
Erping Long
Principal Investigator，Home for Cataract Children, Zhongshan Ophthalmic Center
Sun Yat-sen University