Ultrasound-guided Adductor Canal Block for Total Knee Replacement: a Randomized, Double-blind Placebo Controlled Trial.
Overview
- Phase
- Phase 4
- Intervention
- Bupivacaine
- Conditions
- Complications; Arthroplasty
- Sponsor
- Northwestern University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Opioid Consumption (mg morEq)
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.
Detailed Description
The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.
Investigators
Antoun Nader
Professor of Anesthesiology
Northwestern University
Eligibility Criteria
Inclusion Criteria
- •Participants 40 to 75 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia
Exclusion Criteria
- •Patient refusal
- •American Society of Anesthesiologists physical status classification of 4 or higher
- •Pre-existing neuropathy in the femoral or sciatic distribution
- •Coagulopathy
- •Infection at the site
- •Chronic opioid use (greater than 3 months)
- •Pregnancy
- •Medical conditions limiting physical therapy participation
- •Any other contra-indication to regional anesthesia
Arms & Interventions
Active Group
Ultrasound-guided adductor canal blockade with 10 ml of 0.25% bupivacaine
Intervention: Bupivacaine
Control Group
Ultrasound-guided sham block with 10 ml of preservative free normal saline
Intervention: Preservative free normal saline
Outcomes
Primary Outcomes
Opioid Consumption (mg morEq)
Time Frame: 36 hours
Opioid consumption (morphine equivalents)
Secondary Outcomes
- Length of Hospitalization(0 to 192 hours)
- Visual Analog Scale Pain Score(Pain burden at 36hr)