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Clinical Trials/NCT04325971
NCT04325971CompletedNot Applicable

Study of Eye Movements as Markers of the Physiological, Cerebral and Cognitive State of Healthy Subjects

University Hospital, Grenoble2 sites in 1 country45 target enrollmentStarted: September 16, 2020Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
45
Locations
2
Primary Endpoint
Eye movement brain networks

Study Overview

Brief Summary

The goal of this study is the multimodal exploration via eyetracking, MRI and EEG data of ocular movements and the corresponding brain activation during ecologic visual stimulation in the healthy population.

Detailed Description

Cerebral activation following visual stimulation is explored using two neuroimaging techniques EEG and MRI while eye movements are recorded. Three experiments are performed: in MR scanner 1) functional localisation of specific areas: LOC, FFA, MT/V5, V1 and V2 and 2) a saccadic choice experiment; with EEG, replication of the experiments performed in the MR scanner and 3) an additional experiment of movement detection during the ocular saccades.

Thirty young volunteers (18-40 y old) are involved.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Basic Science
Masking
None

Masking Description

anonymisation of all data

Eligibility Criteria

Ages
18 Years to 40 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Normal vision or corrected to normal
  • Social security affiliation
  • Signed consent to participate
  • No pregnancy fo women

Exclusion Criteria

  • Audition and motor troubles
  • Incapable to decide (Persons mentioned in L1121-5,6 et 8 of public health code)
  • Neurological disorders
  • Pathology affecting oculomotor control
  • MRI incompatibility

Outcomes

Primary Outcomes

Eye movement brain networks

Time Frame: 24 months

Identification of the cerebral locus of ocular movement via MRI \& EEG

Secondary Outcomes

  • OculoDB(24 months)

Investigators

Sponsor
University Hospital, Grenoble
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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