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Study of Eye Movements as Markers of the Physiological, Cerebral and Cognitive State of Healthy Subjects

Not Applicable
Completed
Conditions
Healthy
Interventions
Other: Neuroimaging
Registration Number
NCT04325971
Lead Sponsor
University Hospital, Grenoble
Brief Summary

The goal of this study is the multimodal exploration via eyetracking, MRI and EEG data of ocular movements and the corresponding brain activation during ecologic visual stimulation in the healthy population.

Detailed Description

Cerebral activation following visual stimulation is explored using two neuroimaging techniques EEG and MRI while eye movements are recorded. Three experiments are performed: in MR scanner 1) functional localisation of specific areas: LOC, FFA, MT/V5, V1 and V2 and 2) a saccadic choice experiment; with EEG, replication of the experiments performed in the MR scanner and 3) an additional experiment of movement detection during the ocular saccades.

Thirty young volunteers (18-40 y old) are involved.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
45
Inclusion Criteria
  • Normal vision or corrected to normal
  • Social security affiliation
  • Signed consent to participate
  • No pregnancy fo women
Exclusion Criteria
  • Audition and motor troubles
  • Incapable to decide (Persons mentioned in L1121-5,6 et 8 of public health code)
  • Neurological disorders
  • Pathology affecting oculomotor control
  • MRI incompatibility

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Healthy SubjectsNeuroimagingAll healthy subject are gathered in one arm
Primary Outcome Measures
NameTimeMethod
Eye movement brain networks24 months

Identification of the cerebral locus of ocular movement via MRI \& EEG

Secondary Outcome Measures
NameTimeMethod
OculoDB24 months

Database repository of healthy population

Trial Locations

Locations (1)

Chu Grenoble Alpes

🇫🇷

Grenoble, France

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