Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestatio

Completed

• Conditions: Medical abortion; Pregnancy and Childbirth; Abortion

• Registration Number: ISRCTN18011364
• Lead Sponsor: Hong Kong Health Services Research Fund (Hong Kong)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2002-10-14
• Last Update Posted: 2015-01-13

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

1. The duration of menstrual delay is less than 49 days
2. The size of the uterus on pelvic examination is compatible with the estimated duration of pregnancy
3. A positive pregnancy test
4. There is no history of significant medical illness
5. Age greater than 16 years old
6. Requests legal termination of pregnancy

Exclusion Criteria

1. History or evidence of disorders that represent a contraindication to the use of misoprostol (mitral stenosis, glaucoma, sickle cell anaemia, diastolic pressure >100 mm Hg, bronchial asthma)
2. History or evidence of thrombo-embolism, severe or recurrent liver disease or pruritus of pregnancy
3. Presence of intrauterine contraceptive device (IUCD) in utero
4. Suspect or proven ectopic pregnancy
5. Heavy smoker (smoking >10 cigarettes daily in the past 2 years) or had another risk factor for cardiovascular disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified