Assessment of Lung Functions in Menopausal Obese Women After COVID 19 Recovery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Forced expiratory volume in the first second (FEV1)
研究概览
简要总结
The COVID-19 pandemic has presented considerable challenges to global health services and dictates almost every aspect of medical practice and policy. The menopausal transition may have significant consequences for respiratory health as COVID 19 symptoms subsides, lung function testing should be done to assess the consequences of this virus on lung health especially in menopausal woman.
详细描述
The study group will consist of (40) obese menopausal women whom were recently recovered from mild-moderate COVID 19 for one month. The control group will consist of (40) obese menopausal women; whom will not affected by COVID 19. Using incentive spirometer, we will measure forced vital capacity FVC, forced expiratory volume FEV, Tiffano index TI and peak expiratory force PEF in both groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Participants recovered from mild to moderated signs and symptoms of COVID- 19 after one month.
- •Ability to perform pulmonary function tests correctly.
- •COVID-19 was diagnosed by positive polymerase chain reaction (PCR) testing on nasopharyngeal swab, oxygen saturation was ranged between 92-96% during illness period.
- •CT chest shows ground glass opacity.
- •Their D-dimer was less than 0.5 μg/ml.
- •Two successive negative PCR were before included in study.
- •Participants were in home isolation during illness period.
排除标准
- •Chronic respiratory disease.
- •Chronic heart disease.
- •Diabetes mellitus.
- •Centralized isolation.
- •Severe COVID-19.
结局指标
主要结局
Forced expiratory volume in the first second (FEV1)
时间窗: FEV1 will be measured after 1 month post COVID19 recovery.
is a measurement of your ability to expel air from your lungs. More specifically, and as its name suggests, it is the amount that is exhaled in the first second of purposefully trying to breathe out as much air as possible.
forced vital capacity (FVC)
时间窗: FVC will be measured after 1 month post COVID19 recovery.
is the total amount of air exhaled during the FEV test.
FEV1/FVC ratio
时间窗: FEV1/FVC ratio will be measured after 1 month post COVID19 recovery.
The FEV1/FVC ratio, also called Tiffeneau-Pinelli index, is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease. It represents the proportion of a person's vital capacity that they are able to expire in the first second of forced expiration to the full, forced vital capacity.
次要结局
未报告次要终点
研究者
Hend Reda Sakr
Lecturer at Department of Physical Therapy for Woman's Health
Badr University