Effect of supplementation with a synbiotic on the inflammatory response in children and adolescents with cystic fibrosis

Not Applicable

• Conditions: Cystic fibrosis; Gastrointestinal Microbioma; C06.689.202; G06.591.375

• Registration Number: RBR-5byrsc
• Lead Sponsor: niversidade Federal de Santa Catarina

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-11
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Cystic fibrosis group: Children and adolescents up to and including age zero and less than or equal to 15 years; to present a diagnosis of HR based on the sweat test (sweat chloride 60 mmol / L); clinically at least 30 days prior to data collection. For controls without cystic fibrosis: children and adolescents aged 0 years and 15 years without cystic fibrosis; clinically stable at least 30 days prior to data collection

Exclusion Criteria

Subjects with fever, trauma, inflammatory diseases (asthma, inflammatory bowel disease, rheumatic disease), psychiatric, degenerative, cardiovascular, diabetes, glucose intolerance, renal failure, primary or secondary immunodeficiency Subjects undergoing antibiotic use at baseline, hormones, non-hormonal anti-inflammatory drugs, immunosuppressants and antihistamines, up to 30 days prior to data collection and subjects in pulmonary exacerbation

Study & Design

• Study Type: Intervention
• Study Design: Not specified