A multicenter phase II trial of peri-operative chemotherapy with mFOLFOX6 for resectable liver metastases from colorectal cancer.
- Conditions
- colorectal cancer
- Registration Number
- JPRN-UMIN000009725
- Lead Sponsor
- 3rd department of surgery Tokyo Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Not provided
1. Serious drug hypersensitivity or a history of drug allergy 2. Peripheral neuropathy 3. Active concomitant malignancy 4. Severe infectious disease 5. Serious complications (renal failure or hepatic failure) 6. High blood pressure and diabetic and hypercalcemia that cannot be controlled 7. Symptomatic or asymptomatic but treated heart disease 8. Symptomatic or asymptomatic but treated heart disease 9. Histry of mental disturbances or cerebrovascular attack 10. Fresh hemorrhage from digestive tube, intestines tube paralysis, intestinal obstruction and peptic ulcer 11. Plerral effusion, peritoneal fluid and pericardial fluid 12. Symptomatic brain metastasis 13. Water solubility diarrhea, in case of the patient who has a colostomy, diarrhea impairs daily life activity 14. Under coutinuous steroid therapy 15. History of organ transplantation 16. Traumatic gracture of unrecovery 17. Pregnant women, possibly pregnant women, wishing to become pregnant, and nursing mothers 18. Other conditions not suitable for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method