Gastric Venous Reconstruction to Reduce Gastric Venous Congestion After Total Pancreatectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 3
- 主要终点
- Incidence of gastric venous congestion
研究概览
简要总结
Total pancreatoduodenectomy (TP) is the standard surgical approach for treatment of extended pancreas tumors. If the gastric coronary vein has to be sacrificed for oncologic or for technical reasons in total pancreatectomy with splenectomy, gastric venous congestion (GVC) may result because all major venous draining routes are terminated. In the sequelae of GVC, gastric venous infarction ultimately leads to gastric perforation with abdominal sepsis. To avoid gastric venous infarction, partial or even total gastrectomy is usually performed in the event of GVC after TP. However, this significantly impacts the patient's quality of life.
Reconstruction of gastric venous outflow represents a technical approach to overcome GVC and to avoid gastric venous infarction making (partial) gastrectomy unnecessary. The current study aims to assess the role of gastric venous outflow reconstruction in GVC after TP to prevent (partial) gastrectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Provide written informed consent
- •Elective total pancreatectomy for malignant or benign pancreatic lesions or chronic pancreatitis with splenectomy
- •Intraoperative ligation of coronary vein
排除标准
- •Gastric resection due to malignant infiltration
- •Non-reconstructable gastric venous drainage
- •Previous pancreas surgery
结局指标
主要结局
Incidence of gastric venous congestion
时间窗: 30 days postoperative
Gastric venous congestion after gastric venous reconstruction following total pancreatectomy
Reoperation rate
时间窗: 30 days postoperative
Reoperation rate after gastric venous reconstruction following total pancreatectomy
Morbidity rate
时间窗: 30 days postoperative
Complications rate after gastric venous reconstruction following total pancreatectomy
Incidence of gastric ischemia
时间窗: 30 days postoperative
Gastric ischemia after gastric venous reconstruction following total pancreatectomy
Postpancreatectomy gastrectomy rate
时间窗: 30 days postoperative
Rate of gastrectomy after gastric venous reconstruction following total pancreatectomy
Mortality rate
时间窗: 30 days postoperative
Mortality rate after gastric venous reconstruction following total pancreatectomy
次要结局
未报告次要终点
研究者
Arianeb Mehrabi, MD
Professsor, Head of the Division of Liver Surgery and Visceral Transplantation
University Hospital Heidelberg