Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease

• Conditions: Ischemic Stroke

• Registration Number: NCT02720861
• Lead Sponsor: Chulalongkorn University

Brief Summary

To explore the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease in Thai patients.

Detailed Description

This is an cross-sectional observational study in Chulalongkorn hospital, to determine the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease. Patients who are potentially eligible for study participation will be identified through a chart review of patients who were admitted in Chulalongkorn Hospital for acute ischemic stroke treatment.

Study Timeline

• Study Start: 2015-03
• Status Verified: 2016-03
• Primary Completion: 2016-03
• Study First Submitted: 2016-03-15
• Study First Submitted QC: 2016-03-25
• Last Update Submitted: 2016-03-25
• Study First Posted: 2016-03-28
• Last Update Posted: 2016-03-28
• Study Completion: 2016-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Nationality in Thailand
• Age equal or more than 18 years
• Clinical and imaging diagnosis of acute ischemic stroke
• Patient consent to participate in the research

Exclusion Criteria

• High risk for cardioembolic stroke by TOAST classification
• Contraindication for venipuncture
• Pregnancy or breast feeding patient
• History of head and neck radiation
• Down's syndrome
• Marfan syndrome
• Autoimmune disease such as SLE
• Ongoing malignancy or remission of malignancy less than 1year

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of Participants With RNF213 rs112735431 Gene polymorphism	1 year

Trial Locations

Locations (1)

Suporn Travanichakul; 🇹🇭 Bangkok, Thailand