Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease: A Cross-sectional Study in Thai Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Number of Participants With RNF213 rs112735431 Gene polymorphism
研究概览
简要总结
To explore the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease in Thai patients.
详细描述
This is an cross-sectional observational study in Chulalongkorn hospital, to determine the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease. Patients who are potentially eligible for study participation will be identified through a chart review of patients who were admitted in Chulalongkorn Hospital for acute ischemic stroke treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Nationality in Thailand
- •Age equal or more than 18 years
- •Clinical and imaging diagnosis of acute ischemic stroke
- •Patient consent to participate in the research
排除标准
- •High risk for cardioembolic stroke by TOAST classification
- •Contraindication for venipuncture
- •Pregnancy or breast feeding patient
- •History of head and neck radiation
- •Down's syndrome
- •Marfan syndrome
- •Autoimmune disease such as SLE
- •Ongoing malignancy or remission of malignancy less than 1year
结局指标
主要结局
Number of Participants With RNF213 rs112735431 Gene polymorphism
时间窗: 1 year
次要结局
未报告次要终点
研究者
Suporn Travanichakul, MD.
Neurology Division of Chulalongkorn hospital
Chulalongkorn University
