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Comparison of Meniscus Extrusion Between Preoperative and Postoperative MOWHTO Using Ultrasonographic Assessment

Conditions
Osteoarthritis, Knee
Registration Number
NCT04719195
Lead Sponsor
The Catholic University of Korea
Brief Summary

The purpose of this study is to measure the changes in the medial and lateral meniscus extrusion of the knee joint before and after surgery using ultrasound in patients who undergo medial opening wedge high tibial osteotomy, and examine the differences.

Detailed Description

High tibial osteotomy (HTO) is an established treatment method for medial compartment osteoarthritis with varus knee deformity in a relatively young patient group. Excellent outcomes of HTO have been reported. However, about 10-30% of patients are not satisfied with the results after surgery. After proximal tibial osteotomy, studies on the factors of dissatisfaction have been actively conducted, but studies on the medial and lateral meniscus extrusion, which can be the cause, are insufficient. The relationship between the prolapse of the medial meniscus and articular cartilage is already well known and is known as an important factor in the progression of arthritis. As such, the association between the knee joint with meniscus extrusion and the general knee joint has been studied, but the effect on the clinical outcome after proximal tibial osteotomy has not been studied. Therefore, in this study, the investigators are planning to investigate the differences in clinical outcomes such as the degree and change of medial and lateral meniscus extrusion through non-invasive ultrasound examination before and after surgery in patients who undergo medial open proximal tibial osteotomy.

This study will enroll the patients with knee medial compartment osteoarthritis of the knee joint who undergo open proximal tibial osteotomy. The degree of medial and lateral meniscus extrusion will be measured through ultrasound measurements before and after surgery. Also, demographic factors and radiographic measurements will be also investigated before and after surgery. In addition, preoperative, postoperative 3, 6, and 1 year clinical results including meniscus extrusion will be compared and judged, and the evaluation will be evaluated by an orthopedic surgeon who has not participated in the operation among registered researchers.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Adults over 20
  • Medial compartment knee osteoarthritis patients for Medial Opening Wedge High Tibial Osteotomy
  • Patients who are willing or able to follow doctor's instructions, including joint exercises
  • Patients who have received sufficient explanation for this clinical trial and agreed to participate
Exclusion Criteria
  • Patients with secondary knee osteoarthritis
  • Patients with inflammatory arthritis or crystalline arthritis
  • Local infection to the lower extremities of the pain area, sepsis, or previous neurological abnormalities.
  • Patients with knee range of motion less than 90 degrees
  • Patients with BMI above 40

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
WOMAC(Western Ontario and McMaster University Arthritis Index ) pain scalechanges from pre-operative WOMAC score at post-operative 3rd month, 6th month and 1 year
Secondary Outcome Measures
NameTimeMethod
Pain Visual Analogue Scalechanges from pre-operative VAS score at post-operative 3rd month, 6th month and 1 year
SF-12(Short Form heath survey) scorechanges from pre-operative SF-12 score at post-operative 3rd month, 6th month and 1 year
EQ-5D(EuroQoL-5 Dimension)changes from pre-operative EQ-5D score at post-operative 3rd month, 6th month and 1 year
X-raychanges from pre-operative weight bearing line ratio at post-operative 3rd month, 6th month and 1 year

weight bearing line ratio

Knee range of motionchanges from pre-operative knee range of motion at post-operative 3rd month, 6th month and 1 year
Ultrasonographic evaluation of medial and lateral meniscus extrusionchanges from pre-operative ultrasonographic evaluation of medial and lateral meniscus extrusion at post-operative 3rd month, 6th month and 1 year

Trial Locations

Locations (1)

the Catholic Univerisity of Korea Seoul St Mary's hospital

🇰🇷

Seoul, Korea, Republic of

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