跳至主要内容
临床试验/NCT04740983
NCT04740983Unknown不适用

The Study of Efficacy and Safety of UV Forecasting Based Heliotherapy For Psoriasis in Bangkok, Thailand: A Split-side Pilot Study

Chulalongkorn University0 个研究点目标入组 20 人开始时间: 2021年3月15日最近更新:
适应症

试验速览

阶段
不适用
入组人数
20
主要终点
Changes of Targeted PASI score

研究概览

简要总结

Due to limited number of phototherapy centres and shortage of qualified phototherapy practitioners, heliotherapy has become a promising treatment alternative in Thailand where patients effortlessly receive supervised sun-bathing treatments from their homes whenever they are convenient. We used newly designed deep neural network UV forecasting model developed by using our 10 year-retrospective Solar UV irradiance (280-400 nm) retrieved from a ground based platform at Atmosperic laboratory, Silpakorn University, Nakhon Pathom, Thailand (13.82N 100.04E, 30 m above mean sea level). This model achieved a next-day forecast error of less than 12% which has been the most accurate prediction to date. We designed our 10week heliotherapy regimen based on the predicted anti psoriasis effective irradiance values. We studied efficacy and safety of the 12-week heliotherapy regimen for psoriasis on only ruled acceptable clear sky days in Bangkok, Thailand

详细描述

We studied efficacy and safety of the 16-week heliotherapy regimen for psoriasis on only ruled acceptable clear sky days in Bangkok, Thailand

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Double (Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • A psoriasis patient who indicate to have phototherapy and have lesional plagues systemically either on the front-back or left-right.
  • A participant is based in Bangkok
  • A participant is capable to understand and learn how to use our in-house assembled UV metre and web-based heliotherapy platform.

排除标准

  • A participant has any sun-sensitive conditions including photo-aggravated photodermatoses and on photosentisitive drug treatments.
  • Breast-feeding, pregnant individuals.

结局指标

主要结局

Changes of Targeted PASI score

时间窗: 16 weeks

PASI score for targeted plagues will be evaluated by two independent dermatologists (EB, PA) from standard digital photographs.

次要结局

  • Incidence of possible acute side effects after sun bathing(16 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Einapak Boontaveeyuwat, MD

Consultant dermatologist, Dr.

Chulalongkorn University

相似试验