To understand the difference in bleeding after tooth removal in patients taking blood thinner medication (Aspirin 75 or 150mg) compared to those not taking the medication.

Phase 4

Conditions: Health Condition 1: K029- Dental caries, unspecified

Registration Number: CTRI/2024/02/062261

Lead Sponsor: Dr Mehul Saha

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Patients who are on single therapy of daily low-dose Aspirin 75mg or 150mg.

2. Patients who are more than 18 years and fall in ASA I or well controlled ASA II category.

3. Patients who need to undergo single tooth extraction by closed method under local anaesthesia in an OPD setting.

4. Patients who live within 25 km radius of the hospital.

5. Patients who give written consent to participate in the study.

Exclusion Criteria

1. Patients who are less than 18 years and fall in uncontrolled ASA II, ASA III, ASA IV and ASA V category.

2. Patients who have undergone PTCA procedure within the last 1 year or had history of CVA or MI within the last 6 months.

3. Patients who are on dual anti-coagulant therapy such as along with clopidogrel, heparin, warfarin or any other new-age anti-coagulants and other medications such as birth control pills, hormone replacement therapy, NSAIDs that can interact with Aspirin.

4. Patients with history of bleeding disorders, alcoholism and pregnant patients.

5. Patients who have to undergo major oral surgical procedures such as multiple teeth extraction, transalveolar extraction, large, multi-site biopsies and all other procedures that warrant ward admission and OT care.

6. Patients who live beyond 25 km radius of the hospital.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To assess the incidence of bleeding after minor oral surgery (single tooth extraction) in patients taking daily low-dose Aspirin 75 - 150mg during the procedure, at 24 hours and at 48 hours after the procedure. <br/ ><br>2. To assess the incidence of bleeding after minor oral surgery (single tooth extraction) in patients who have stopped oral anti-platelets 5 days prior to procedure during the procedure, at 24 hours and at 48 hours after the procedure.Timepoint: 1. To assess the incidence of bleeding after minor oral surgery (single tooth extraction) in patients taking daily low-dose Aspirin 75 - 150mg during the procedure, at 24 hours and at 48 hours after the procedure. <br/ ><br>2. To assess the incidence of bleeding after minor oral surgery (single tooth extraction) in patients who have stopped oral anti-platelets 5 days prior to procedure during the procedure, at 24 hours and at 48 hours after the procedure.

Secondary Outcome Measures