The efficacy of preemptive gabapentin for pain reduction after gynecologic surgery
Phase 4
Completed
- Conditions
- Preemptive gabapentin 600 mg for pain reduction after gynecologic surgery compare with placebo-
- Registration Number
- TCTR20170809002
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 36
Inclusion Criteria
1)body mass index below or equal 35 kg/m2
3)American Society of Anesthesiologists physical status (ASA) classification class I-II
4)Appointment to explore laparotomy for gynecologic surgery include total abdominal hysterectomy(TAH) with or without oophorectomy, salpingectomy, omentectomy, or lymphadenectomy
5)General anesthesia
6)Understand and can use visual analogue scale (VAS)
7)Understand and can use patient controlled analgesia (PCA)
Exclusion Criteria
1)Allery to gabapentin or opioid
2)underlying disease of epilepsy, psychiatric disease, or chronic pain
3)Use addictive substance or analgesic within 48 hours before surgery
4)Ovarian or fallopian tube cancer
5)Expect for long operation than 4 hours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative pain score 2,4,8,12,24 hours after gynecologic surgery Visual analogue scale (VAS)
- Secondary Outcome Measures
Name Time Method Total morphine use(mg) 24 hours after operation 24 hours after operation Patient controlled analgesia (PCA) with morphine (mg),Side effect of morphine or gabapentin use(nausea,vomiting,dizziness,headache,fatigue,pruritis,etc) Within 24 hours after gynecologic surgery Observation and questionaire