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Immediate Effects of High-intensity Laser Therapy on Knee Joint Position Sense and Knee Muscle Strength in Patients with Knee Osteoarthritis

Phase 2
Completed
Conditions
Knee Osteoarthritis
Interventions
Device: high-intensity laser therapy
Device: Sham-HILT
Registration Number
NCT06632119
Lead Sponsor
Mahidol University
Brief Summary

The goal of this clinical trial is to compare whether HILT versus Sham-HILT is effective to reduce pain, improve knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Detailed Description

The investigators would like to investigate whether single session of high-intensity laser therapy (HILT) is promising to see the changes in individuals with knee osteoarthritis (KOA)-related knee pain regarding pain intensity, knee joint position sense, and knee muscle strength.

The objectives of this study is to compare pre and post, and between the two groups (HILT versus Sham-HILT) at after interventions regarding pain, knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT by an experienced musculoskeletal physical therapist, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
10
Inclusion Criteria
  • knee pain greater than 3 on the Visual Analog Scale (VAS) for more than 3 months
  • diagnosed with unilateral knee osteoarthritis by a physician or meeting the American College of Rheumatology Classification Criteria for clinical knee osteoarthritis
  • the severity of knee osteoarthritis is classified as grades 0-3 according to the Kellgren-Lawrence (KL) classification
  • should not have undergone any specific treatments in the 3 months preceding the recruitment for the study, such as steroid injections.
Exclusion Criteria
  • any other musculoskeletal problems associated with knee pain
  • musculoskeletal problems associated with the hip and ankle joints
  • a history of lower limb fracture
  • neurological conditions
  • contraindications for laser therapy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
HILThigh-intensity laser therapyhigh-intensity laser therapy (HILT)
Sham_HILTSham-HILTSham-HILT, the HILT without laser release
Primary Outcome Measures
NameTimeMethod
Knee joint position senseBaseline, immediately after, 24-hour after intervention

Knee joint position sense, the investigators used the joint position repositioning technique. The participants were measured for joint position reposition technique with a smartphone application "Measure App" (iPhone 12 Pro Max, Apple Inc., USA). The smartphone attached at shank of tibia bone at the malleolar level. The participants sat in the starting position knee flexion 90°. Then the participants with eyes closed were actively guided to the knee flexion 45 degrees and hold for 3 seconds. The data was recorded the difference between performed position and targeted position.

Secondary Outcome Measures
NameTimeMethod
Knee muscle strengthBaseline, immediately after, 24-hour after intervention

The muscle strength measured both quadriceps and hamstring muscles by the handheld dynamometer at 90°.

PainBaseline, immediately after, 24-hour after intervention

The participants rated the pain scores using a 10-cm visual analog scale (VAS) ranged from 0 "no pain at all" on the left end to 10 "worst pain imaginable" on the right end.

Trial Locations

Locations (1)

Physical Therapy

🇹🇭

Salaya, Nakhon Pathom, Thailand

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