NCT07353320
Completed
Not Applicable
Effects of Probiotics on Alleviating Anxiety and Depression and Gut Microbiota
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Wecare Probiotics Co., Ltd.
- Enrollment
- 79
Overview
Brief Summary
This study is a randomized, double-blind, placebo-controlled trial aimed primarily at investigating the effects of Weizmannia coagulans BC99 on alleviating anxiety and depression and the gut microbiota.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Masking Description
Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Adults aged 18-65 years.
- •Individuals experiencing scientific research, employment-related, or occupational stress, including graduate students or community-dwelling adults with job-related pressure.
- •A Hamilton Depression Rating Scale (HAMD-17) score ≥ 8 and/or a Hamilton 4) Anxiety Rating Scale (HAMA-14) score ≥ 7 at screening.
- •Ability and willingness to voluntarily participate in the study and to provide written informed consent prior to enrollment.
Exclusion Criteria
- •A confirmed previous diagnosis of other psychiatric disorders, including intellectual disability, bipolar disorder, treatment-resistant depression, or suicidal ideation.
- •Pregnant or breastfeeding women.
- •Individuals with known food or drug allergies, or those with alcohol abuse or psychotropic substance abuse.
- •Use of antibiotics or probiotics known to affect gut microbiota for more than one week within one month prior to enrollment.
- •Participants who withdrew from the study, discontinued intervention, or were unable to complete the study for any reason.
Investigators
Similar Trials
Completed
Not Applicable
Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic DisordersNCT07268729University of Toronto500
Enrolling By Invitation
Not Applicable
Probiotics in COPD: Effects on Symptoms, Lung Function, and InflammationNCT07339280University Hospital of Split60
Completed
Not Applicable
Effect of Probiotics on Relapsing-Remitting Multiple SclerosisNCT07346924Cairo University60
Recruiting
Not Applicable
Probiotics in Adults With Rheumatoid ArthritisNCT07304505Ancilia Biosciences50
Completed
Not Applicable
Single Vs Multi-strain Probiotics for Preterm NeonatesNCT07296718Madiha, MPhil249