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临床试验/CTRI/2025/07/091406
CTRI/2025/07/091406尚未招募4 期

Comparative clinical evaluation of Postoperative Pain using 3% Cryotreated Hypochlorite and 0.9% Cryotreated Normal Saline against Conventional root canal treated groups in patients with Symptomatic Irreversible Pulpitis/ Apical Periodontitis after single visit root canal treatment: A Randomized Clinical Study

Dr Aditi Goel1 个研究点 分布在 1 个国家目标入组 69 人开始时间: 2025年8月1日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
69
试验地点
1
主要终点
Postoperative pain

研究概览

简要总结

This study is single centre, double blinded study comparing the postoperative pain after single sitting root canal treatment using either 3% cryotreated Sodium hypochlorite(2°C–4°C) or 0.9% cryotreated normal saline(2°C–4°C) or 3% Sodium hypochlorite and 0.9% normal saline at room temperature along with passive ultrasonic irrigation in patients with symptomatic irreversible pulpitis / apical periodontitis. Clinical evaluation will be done based on postoperative pain after 6 hours, 24 hours , 48 hours and 72 hours using VRS scale.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
16.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Healthy patient who will give informed consent will be included.
  • Single rooted teeth with completely matured root diagnosed with symptomatic irreversible pulpitis / apical periodontitis will be included.
  • Teeth with Peri Apical Index score 2 will be included in the study.

排除标准

  • Teeth with immature roots, those diagnosed with pulp necrosis, cracks, internal/external root resorption or pulp canal obliteration and exhibiting clinical and/or radiographic signs of chronic/severe periodontitis or periapical abscess will be excluded.
  • Patients taking antibiotics, sedatives or analgesics before 24 hrs.
  • of treatment will be excluded.
  • Teeth with previously endodontic treatment will be excluded.
  • Patients with severe periodontitis and poor oral hygiene will be excluded from the study.
  • Pregnant or lactating women will be excluded.

结局指标

主要结局

Postoperative pain

时间窗: 6 hours , 24 hours , 48 hours , 72 hours

次要结局

未报告次要终点

研究者

发起方
Dr Aditi Goel
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Aditi Goel

K.M Shah Dental College and Hospital

研究点 (1)

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