Assessment of Robotic Versus Laparoscopic Gastrectomy for Gastric Cancer Patients With High Surgical Difficulty

Completed

• Conditions: Gastrectomy for Gastric Cancer; Robotic Surgical Procedures; Laparoscopic Surgical Procedures

• Registration Number: NCT06752538
• Lead Sponsor: Fujian Medical University

Brief Summary

While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in high surgical difficulty (HSD) cases remain debated.

Detailed Description

This retrospective cohort study included 3,534 patients with gastric cancer who underwent radical gastrectomy at eight high-volume hospitals. HSD was defined by any of the following criteria: operative time exceeding the third quartile, intraoperative estimated blood loss ≥ 400 mL, or conversion to open surgery. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were conducted to compare short- and long-term outcomes.

Study Timeline

• Study Start: 2016-08
• Primary Completion: 2019-06
• Study Completion: 2024-07
• Status Verified: 2024-12
• Study First Submitted: 2024-12-22
• Study First Submitted QC: 2024-12-22
• Last Update Submitted: 2024-12-22
• Study First Posted: 2024-12-30
• Last Update Posted: 2024-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3534

Inclusion Criteria

• Patients with postoperatively histologically confirmed T1-4aN0-3bM0 gastric adenocarcinoma who underwent RG or LG

Exclusion Criteria

• Remnant gastric cancer
• Previous malignant
• ASA class >3
• Use of indocyanine green
• Neoadjuvant chemotherapy
• Loss to follow-up
• Combined resection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival	Within 3 years after surgery	Telephone follow-up

Secondary Outcome Measures

Name	Time	Method
recurrence	36 months	Telephone follow-up
Postoperative complications	30 days after surgery	Postoperative complications were evaluated according to the Clavien-Dindo classification and categorized as surgical or medical

Trial Locations

Locations (1)

Fujian Medical University Union Hospital; 🇨🇳 Fuzhou, Fujian, China