The roles of occipital and parietal regions in visual awareness: A Transcranial Magnetic Stimulation study
Recruiting
- Conditions
- niet van toepassingnvt
- Registration Number
- NL-OMON33292
- Lead Sponsor
- Radboud Universiteit Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Right-handed individuals, with normal or corrected-to-normal vision and no history of neurological or psychological disorders are included.
Exclusion Criteria
- Pacemaker
- Metal parts in head or mouth
- History of brain surgery
- History of epilepsy or first-grade family member with epilepsy
- Psychological or neurological disorder
- Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The effect of TMS on the three stimulation sites in the main experiment will be<br /><br>assessed using a visual task performed in an fMRI scanner. We will test whether<br /><br>stimulation to V1, PPC, and vertex differentially affected subjects* visibility<br /><br>ratings. We predict that V1 stimulation will lead to decrease in visibility<br /><br>ratings for gratings presented anywhere in the visual field, while PPC<br /><br>stimulation will only affect the visibility of gratings in the contralateral<br /><br>visual field. Vertex stimulation is not expected to have any effects on<br /><br>visibility ratings. Further, we predict that the changes in visibility rating<br /><br>will be mediated by changes in the activation patterns in the prefrontal cortex<br /><br>and will test for that in the fMRI part of the experiment.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The effectiveness of TMS stimulation will be assessed in a pilot experiment. We<br /><br>will test whether stimulation to V1, PPC, and vertex differentially affected<br /><br>subjects* visibility ratings. Again, we predict that V1 stimulation will lead<br /><br>to decrease in visibility ratings for gratings presented anywhere in the visual<br /><br>field, while PPC stimulation will only affect the visibility of gratings in the<br /><br>contralateral visual field. Vertex stimulation is not expected to have any<br /><br>effects on visibility ratings. In the pilot experiment we will only collect<br /><br>behavioural data in order to assess the effectiveness of TMS.</p><br>