The effect of Morus nigra extract on patients with liver cirrhosis
Phase 2
- Conditions
- iver cirrhosis.Fibrosis and cirrhosis of liver
- Registration Number
- IRCT20140301016776N3
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients with liver cirrhosis awaiting liver transplantation
Exclusion Criteria
Hepatocellular carcinoma or other malignancy
History of liver transplantation
Alcoholic drink
Variceal bleeding
Portal vein thrombosis
Pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MELD index. Timepoint: Before intervention and end of the study. Method of measurement: The MELD index is determined by total bilirubin, serum creatinine, and INR (9.57 Ln(Creat) + 3.78 Ln(bili) + 11.2 Ln(INR) + 6.43).
- Secondary Outcome Measures
Name Time Method Child-Pugh. Timepoint: before intervention and at the end of study. Method of measurement: This index is calculated based on total bilirubin, albumin, INR, ascites and encephalopathy.;Patient survival. Timepoint: One year after enrollment. Method of measurement: Record the number of patient deaths.;Liver enzymes. Timepoint: Before intervention and at the end of study. Method of measurement: Fasting blood test.