Neglect Treatment by Prism Adaptation in the Acute Phase
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Unilateral Spatial Neglect
- Sponsor
- University of Geneva, Switzerland
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- Unilateral spatial neglect
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This project aims at unveiling the beneficial effects of prism adaptation as early rehabilitation technique to treat unilateral spatial neglect in the acute phase after a brain damage. This syndrome, frequent and very invalidating for daily life activities after a brain damage, is a cognitive disorder of lack of attention towards a part of the space. Patients at a first event brain injury hospitalized into the Neurology and Neurosurgery Departments and affected by spatial neglect will undergo to a protocol of five consecutive rehabilitation treatments, being assigned to the experimental (prisms) or control groups (neutral prisms). The effectiveness of the treatment will be assessed with cognitive, functional and motor-related measures, as well as a follow up 3 months later. These results can have a strong impact on the long-term functional outcome of these patients.
Investigators
Roberta Ronchi
Principal Investigator
University of Geneva, Switzerland
Eligibility Criteria
Inclusion Criteria
- •First neurological event, affecting the right hemisphere or the left hemisphere (stroke, brain tumour post-surgery);
- •Structural images of the brain lesion available (magnetic resonance or tomographic scans);
- •Good Normal (or corrected) visual acuity;
- •Presence of USN, as assessed by a standard neuropsychological evaluation.
Exclusion Criteria
- •Previous neurological disorder and/or current or previous psychiatric disease.
- •Presence or suspicion of previous general cognitive deficits documented from the clinical dossier and/or suspicious of possible cognitive deficits ;
- •Presence of difficulty in task's comprehension preventing its completion;
- •Impossibility to sustain a research session of at least 30 minutes (e.g., attentional lability).
Outcomes
Primary Outcomes
Unilateral spatial neglect
Time Frame: Day 0; Day 5; 12 weeks after the end of the protocol
Scores in the neuropsychological tasks administered just before and after the rehabilitation protocol: BEN battery, with the number of lateralized omissions in target cancellation, drawing and reading; bisection bias for the line bisection test
Disability measures
Time Frame: Day 0; Day 5; 12 weeks after the end of the protocol
Scale for assessing disability after stroke just before and after the rehabilitation protocol: FIM (range 18-126)
Functional measures
Time Frame: Day 0; Day 5; 12 weeks after the end of the protocol
Scores in the functional test testing USN administered just before and after the rehabilitation protocol: CBS scale, evaluating the impact of neglect in 10 daily living activities (range 0-30)
Balance
Time Frame: Day 0; Day 5; 12 weeks after the end of the protocol
Balance tests after stroke just before and after the rehabilitation protocol: PASS (range 0-36)
Secondary Outcomes
- Functional Measures: Right vs. Left neglect(Day 5; 12 weeks after the end of the protocol)
- Neuropsychological tests: Right vs. Left neglect(Day 5; 12 weeks after the end of the protocol)
- Disability Measures: Right vs. Left neglect(Day 5; 12 weeks after the end of the protocol)
- Balance: Right vs. Left neglect(Day 5; 12 weeks after the end of the protocol)
- Functional Measures: Follow-up(12 weeks after the end of the protocol)
- Balance: Follow-up(12 weeks after the end of the protocol)