MedPath

Improving FAMily Members' Experience in the ICU

Completed
Conditions
Stress Disorders, Post-Traumatic
Family Members
Interventions
Other: Health care professionals
Other: Family members of patients admitted to the ICU
Other: Patients
Registration Number
NCT05461521
Lead Sponsor
Nantes University Hospital
Brief Summary

The aim of the present research is to set up a large multicentric, prospective cohort of family members of patients admitted to intensive care. The data collected will concern the patients and their family members, the caregivers and the functioning of the services during the collection period. This cohort will allow:

1. to carry out a quantitative evaluation of post-traumatic stress disorder (PTSD) in a large number of family members, to determine the risk factors in relation to the characteristics of the family members, and to define a predictive model of PTSD in this population

2. to determine the factors related to the operating conditions of the resuscitation services that favor the occurrence of PTSD in the family members,

3. to create a biological bank from blood samples taken from family members,

4. to carry out a qualitative study allowing a psychological and sociological analysis of the experience of the family members concerning the hospitalization in intensive care of their loved one.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1346
Inclusion Criteria

Patients :

  • ≥18 years old
  • Treated in the ICU with invasive mechanical ventilation for 48 hours
  • Having been visited by at least one family member within 72 hours of the 48th hour of intubation in intensive care
  • Having been informed of the study and not having objected to the use of their medical medical data prior to discharge from the ICU if they are able to receive the information the information at the time of inclusion or consent of the family member obtained for the inclusion of the patient if the patient is not able to do so at the time of at the time of inclusion

Family members :

  • ≥18 years old
  • Identified if possible by the patient as the person to be referred or to be informed, or, in the case of a patient unable to express him/herself, identified by the caregivers as the "patient's close referent".
  • Understanding and speaking French
  • Having been informed of the study and having consented to participate in it during a visit of the patient
  • Inclusion between H48 and H120 post-intubation of the patient in the ICU (if the patient is still intubated at the time of inclusion)
  • Having given their telephone number
  • Being covered by a social security plan.
  • Only one relative of the patient is included in the study Service Professionals: All professionals in all categories and in all participating participating services who have been informed of the study and have consented to participate.
Exclusion Criteria

Patients:

  • No family member or no family member visit
  • No consent to participate from family member
  • Organ donation planned or contemplated
  • Pregnant or parturient woman
  • Detained or deprived of liberty
  • Under guardianship or curator
  • No social security

Family members :

  • Social context making follow-up and telephone interviews difficult (homeless, not residing in Europe or in the DOM)
  • Inability to give a "stable" personal cell phone number
  • Under guardianship or curator
  • Unable to communicate on the phone (hearing impairment...)

Service Professionals:

  • Not on duty (locum tenens or interim team, only on-call) on call)
  • Not qualified (Physician: at least intern, nurse DE)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Health care professionalsHealth care professionals-
Family members of patients admitted to the ICUFamily members of patients admitted to the ICU-
PatientsPatients-
Primary Outcome Measures
NameTimeMethod
To define a predictive model of PTSD in this populationat 3 months after the patient's discharge from the ICU

The primary endpoint is the proportion of family members who developed PTSD 3 months after the patient's discharge from the ICU assessed by the Post-traumatic stress disorder CheckList (PCL-5) version Diagnostic and Statistical Manual of Mental Disorders (DSM-5) scale. This scale consists of 20 items on the symptoms of PTSD according to the DSM-5 criteria. Each item is rated from 0 ("not at all") to 4 ("extremely"). The maximum score is 80.

To determine the factors associated with post-traumatic stress disorder (PTSD) in family members of patients admitted to the ICU, and.at 3 months after the patient's discharge from the ICU

The primary endpoint is the proportion of family members who developed PTSD 3 months after the patient's discharge from the ICU assessed by the Post-traumatic stress disorder CheckList (PCL-5) version Diagnostic and Statistical Manual of Mental Disorders (DSM-5) scale. This scale consists of 20 items on the symptoms of PTSD according to the DSM-5 criteria. Each item is rated from 0 ("not at all") to 4 ("extremely"). The maximum score is 80.

Secondary Outcome Measures
NameTimeMethod
To identify the impact on the consumption of care and medical procedures of PTSD in family members of patients admitted to the ICUat 3 and 6 months after discharge of the patient from the intensive care unit

Proportion of relatives who used psychoactive substances assessed by the Who-assist questionnaire (Question 2 of the questionnaire), Consumption of care and medical procedures by relatives (MEDEC questionnaire

Assessing the psychological impact of a family member stay in intensive careat 6 months after the patient's death in intensive care

Proportion of relatives who developed prolonged grief assessed by the Prolonged Grief disorder (PG-13) questionnaire

Trial Locations

Locations (56)

CH Beauvais

🇫🇷

Beauvais, France

CH de Dieppe

🇫🇷

Dieppe, France

CHU de Grenoble Alpes

🇫🇷

Grenoble, France

CH du Mans

🇫🇷

Le Mans, France

AP-HM - Hôpital Nord

🇫🇷

Marseille, France

CHU de Montpellier - Hôpital Lapeyronie

🇫🇷

Montpellier, France

CH de Saint-Malo

🇫🇷

Saint-Malo, France

APHP Hôpital Cochin

🇫🇷

Paris, France

CHU de Bordeaux - Hôpital Pellegrin

🇫🇷

Bordeaux, France

CH de Boulogne-sur-Mer

🇫🇷

Boulogne-sur-Mer, France

AP-HP Hôpital Ambroise Paré

🇫🇷

Boulogne, France

CH de Cholet

🇫🇷

Cholet, France

CHU Clermont-Ferrand - Centre Jean Perrin

🇫🇷

Clermont-Ferrand, France

CHU de Dijon

🇫🇷

Dijon, France

CHD Vendée

🇫🇷

La Roche-sur-Yon, France

CH Versailles - Hôpital André Mignot

🇫🇷

Le Chesnay, France

CHU de Montpellier - Hôpital Saint-Eloi

🇫🇷

Montpellier, France

Clinique Ambroise Paré

🇫🇷

Neuilly-sur-Seine, France

Hôpital Foch

🇫🇷

Suresnes, France

CHU De Lyon - Hôpital Edouard Herriot

🇫🇷

Lyon, France

APHP Hôpital Saint-Antoine

🇫🇷

Paris, France

Hôpital Privé d'Antony

🇫🇷

Antony, France

CH d'Argenteuil

🇫🇷

Argenteuil, France

APHP Hôpital Avicenne

🇫🇷

Bobigny, France

CH Angoulême

🇫🇷

Angoulême, France

CH de Bastia

🇫🇷

Bastia, France

CHU de Brest

🇫🇷

Brest, France

CHU Clermont-Ferrand - Hôpital Gabriel Montpied

🇫🇷

Clermont-Ferrand, France

CH de Fréjus - Saint Raphaël

🇫🇷

Fréjus, France

CHI Poissy

🇫🇷

Poissy, France

CH René Dubos

🇫🇷

Pontoise, France

CH de Saint-Lô

🇫🇷

Saint-Lô, France

CH de Saint-Nazaire

🇫🇷

Saint-Nazaire, France

CH de Tourcoing - Hôpital Guy Chatiliez

🇫🇷

Tourcoing, France

CH de Vichy

🇫🇷

Vichy, France

Hôpital Nord Franche Comté

🇫🇷

Belfort, France

CH de Béthune

🇫🇷

Beuvry, France

CHU de Bordeaux - Hôpital Saint-André

🇫🇷

Bordeaux, France

CH de Chartres

🇫🇷

Chartres, France

APHP Hôpital Raymond Poincaré

🇫🇷

Garches, France

CH de la Rochelle

🇫🇷

La Rochelle, France

Hôpital Privé Jacques Cartier

🇫🇷

Massy, France

CHU de Nantes

🇫🇷

Nantes, France

CHR d'Orléans

🇫🇷

Orléans, France

CH de Bassin de Thau

🇫🇷

Sète, France

Ch Bretagne Atlantique - site de Vannes

🇫🇷

Vannes, France

Institut Gustave Roussy

🇫🇷

Villejuif, France

CHU La Guadeloupe

🇬🇵

Pointe-à-Pitre, France, Guadeloupe

APHP Hôpital La Pitié Salpêtrière

🇫🇷

Paris, France

APHP Hôpital Saint-Louis

🇫🇷

Paris, France

GHEF- Site de Marne de la Vallée

🇫🇷

Jossigny, France

CHU de Lille - Hôpital Roger Salengro

🇫🇷

Lille, France

GHB Sud - Hôpital de Lorient

🇫🇷

Lorient, France

GHI le Raincy Montfermeil

🇫🇷

Montfermeil, France

Hôpital du Pays Salonais

🇫🇷

Salon-de-Provence, France

APHP Hôpital Tenon

🇫🇷

Paris, France

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