NL-OMON43024招募中不适用
Correlation between symptoms and the presence of gluten immunogenic peptides in faeces and urine after single dose gluten provocation in patients with coeliac disease* - Gluten intake, symptoms and detection of gluten in urine and feces
Rijnstate Ziekenhuis0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients with biopsy proven coeliac disease, Marsh IIIA or higher at time of diagnosis, adhering to a gluten-free diet and aged 18 years or older are eligible if:
- •- They report clear symptoms on gluten exposure
- •- They report excellent or no problems with dietary adherence (score 13 or less) on the Celiac Disease Adherence Test (CDAT)(8) (Appendix 2)
- •- They report scores resembling clinical remission (score 30 or less) on the Celiac Symptom Index (CSI)(9) (Appendix 3)
- •- Serum TTG and EMA levels are non-detectable during gluten-free diet
- •- Negative GIP in urine/ faeces at the start of this study
排除标准
- •Patients will be excluded if;
- •- They report other CDAT and/or CSI scores
- •- They are pregnant
- •- They have known gastroenterological co-morbidity
- •- They have malignant disease
- •- They use painkillers or other drugs to reduce symptoms
研究者
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