Optimizing Continuous-flow Left Ventricular Assist Device Settings and Identification of Pump Malfunction - A Comparative Study of Echocardiography and Invasive Hemodynamics

Rigshospitalet, Denmark1 个研究点分布在 1 个国家目标入组 15 人2013年4月

适应症Heart Failure.

概览

阶段: 不适用
干预措施: 未指定
疾病 / 适应症: Heart Failure.
发起方: Rigshospitalet, Denmark
入组人数: 15
试验地点: 1
主要终点: Pulmonary capillary wedge pressure in mmHg.
状态: 已完成
最后更新: 10年前

概览研究者入排标准结局指标研究点相似试验

概览

简要总结

The purpose of the trial is to identify factors which can be used as guidance when optimizing continuous-flow left ventricular assist device (CF-LVAD) settings.

The hypothesis of the study is that pulmonary capillary wedge pressure (PCWP) will change independently of left ventricular end diastolic diameter (LVEDD) when increasing pump speed ie ΔPCWP/RPM ≠ ΔLVEDD/RPM.

The primary combined endpoint of the study is correlation between ΔPCWP and LVEDD slope under ramp testing in a cohort of "continuous-flow left ventricular assist device" heart failure patients.

注册库

clinicaltrials.gov

开始日期

2013年4月

结束日期

2015年10月

最后更新

10年前

研究类型

Observational

性别

All

研究者

发起方

Rigshospitalet, Denmark

责任方

Principal Investigator

主要研究者

Finn Gustafsson

DMSc, Ph.d., Chief Physician.

Rigshospitalet, Denmark

入排标准

入选标准

•Heart failure patients with HeartMate II (HM II) followed as outpatients at The Heart Centre at University Hospital of Copenhagen, Rigshospitalet.
•Age \> 18 years.
•Heart failure in stable phase without the need for intravenous inotropic therapy.
•Ischemic or non-ischemic cardiomyopathy.
•Signed informed consent.